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Topic Area: Drugs/Pharmaceuticals
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Displaying records 11 to 20 of 41 records.
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11. Evaluation of Analytical Methodologies for Non-Intrusive Drug Testing--Supercritical Fluid Extraction of Cocaine from Hair
Topic: Drugs/Pharmaceuticals
Published: 3/1/1999
Authors: J F Morrison, L T Sniegoski, W J Yoo, Alim A Fatah
Abstract: Supercritical fluid extraction (SFE) was investigated as an environmentally friendly alternative to currently used wet chemical procedures in hair drug testing protocols. The SFE behavior of cocaine and its primary metabolite benzoylecgonine was stud ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=30143

12. Evaluation of viability and proliferation profiles on macrophages treated with silica nanoparticles in vitro via plate-based, flow cytometry, and Coulter counter assays
Topic: Drugs/Pharmaceuticals
Published: 9/3/2012
Authors: Simona Bancos, De-Hao D. Tsai, Vincent A Hackley, J L Weaver, Katherine M Tyner
Abstract: Nanoparticles (NPs) are known to interfere with many high throughput cell viability and cell proliferation assays, which complicates the assessment of their potential toxic effects. The aim of this study was to compare viability and proliferation res ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=911765

13. Facile Smiles-type rearrangement in radical cations of N-acyl arylsulfonamides and analogs
Topic: Drugs/Pharmaceuticals
Published: 1/21/2014
Authors: Karl K Irikura, Nino Guram Todua
Abstract: RATIONALE: N-Alkylation of sulfonylbenzamides was reported recently to cause a dramatic and surprising change in electron ionization mass spectrometry (EIMS), leading to a closed-shell base peak. Only an incomplete, speculative mechanism was availabl ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912656

14. Fluorinated Copolymer Nanoparticles for Multimodal Imaging Applications
Topic: Drugs/Pharmaceuticals
Published: 2/18/2010
Authors: Mark M. Bailey, Christine M. Mahoney, Elodie Dempah, Jeffrey M Davis, Matthew Becker, Supang Khondee, Eric J. Munson, Cory J. Berkland
Abstract: Nanomaterials have emerged as valuable tools in biomedical imaging techniques, such as magnetic resonance imaging (MRI), fluorescence, positron emission tomography (PET), and others. Some have been designed to serve as multimodal imaging agents, com ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=902813

15. Guide for the Selection of Drug Detectors for Law Enforcement Applications
Topic: Drugs/Pharmaceuticals
Published: 8/1/2000
Author: Alim A Fatah
Abstract: This document surveys the field of contraband drug detection, with emphasis on different types of drug detection methods available and current commercial sources for detection equipment. The introduction includes background information on the proble ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=30177

16. HIV Structural and Biothermodynamics Databases: A Resource for the Pharmaceutical and Biotechnology Industry
Topic: Drugs/Pharmaceuticals
Published: 8/12/2005
Authors: Talapady N Bhat, Yadu D. Tewari, H Rodriguez, Robert Nathan Goldberg
Abstract: Federal agencies, academia and industries have invested heavily in the development of structural and biothermodynamics data. However, the data are still largely distributed over several public and private archives leading to issues of inadequate inte ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830494

17. Integrated Plastic Microfluidic Devices with ESI-MS for Drug Screening and Residue Analysis
Topic: Drugs/Pharmaceuticals
Published: 5/1/2001
Authors: Y. Jiang, P-C. Wang, Laurie E Locascio, C S. Lee
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=904419

18. Isolation, Purification, and Full NMR Assignments of cyclopamine from Veratrum californicum
Topic: Drugs/Pharmaceuticals
Published: 6/24/2009
Authors: Daniel W Bearden, John E. Oatis, Pam Brunsfeld, James W. Rushing, Peter D. Moeller, Thomas N. Gallien, George W. Cooper
Abstract: The Hedgehog (Hh) signaling pathway is essential for embryogenesis and tissue homeostasis in the adult. However, it may also induce malignancies in a number of tissues when constitutively activated, and it also may have a role in other forms of nor ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=832291

19. Microfluidic preparation of liposomes to determine particle size influence on cellular uptake mechanisms
Topic: Drugs/Pharmaceuticals
Published: 10/3/2013
Authors: Wyatt N Vreeland, Abhay U Andar, Renee R Hood, Don L. DeVoe, Peter W Swaan
Abstract: Purpose: This study investigates the cellular uptake and trafficking of liposomes in Caco-2 cells, using vesicles with distinct average diameters ranging from 40 nm-276 nm. Liposomes were prepared by microfluidic hydrodynamic flow focusing, producing ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913538

20. Microfluidic-Enabled of Liposomes Elucidate Size-Dependent Transdermal Transport
Topic: Drugs/Pharmaceuticals
Published: 3/21/2014
Authors: Wyatt N Vreeland, Renee R Hood, Eric Kendall, Don L. DeVoe, Julia Finkel, Mariana Junqueira, Zenaide Quezado
Abstract: Microfluidic synthesis of small and nearly-monodisperse liposomes is used to investigate the size-dependent passive transdermal transport of nanoscale lipid vesicles. While large liposomes with diameters above 105 nm are found to be excluded from dee ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915017



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