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Displaying records 11 to 20 of 34 records.
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11. Establishment of a Quality Assurance Program for the National Establishment of a Quality Assurance Program for the National Cancer Institute's Chemoprevention Program
Topic: Drugs/Pharmaceuticals
Published: 12/1/1986
Authors: Willie E May, R Schaffer, R.C. Paule

12. Evaluation of Analytical Methodologies for Non-Intrusive Drug Testing--Supercritical Fluid Extraction of Cocaine from Hair
Topic: Drugs/Pharmaceuticals
Published: 3/1/1999
Authors: J F Morrison, L T Sniegoski, W J Yoo, Alim A Fatah
Abstract: Supercritical fluid extraction (SFE) was investigated as an environmentally friendly alternative to currently used wet chemical procedures in hair drug testing protocols. The SFE behavior of cocaine and its primary metabolite benzoylecgonine was stud ...

13. Evaluation of viability and proliferation profiles on macrophages treated with silica nanoparticles in vitro via plate-based, flow cytometry, and Coulter counter assays
Topic: Drugs/Pharmaceuticals
Published: 9/3/2012
Authors: Simona Bancos, De-Hao D. Tsai, Vincent A Hackley, J L Weaver, Katherine M Tyner
Abstract: Nanoparticles (NPs) are known to interfere with many high throughput cell viability and cell proliferation assays, which complicates the assessment of their potential toxic effects. The aim of this study was to compare viability and proliferation res ...

14. Facile Smiles-type rearrangement in radical cations of N-acyl arylsulfonamides and analogs
Topic: Drugs/Pharmaceuticals
Published: 1/21/2014
Authors: Karl K Irikura, Nino Guram Todua
Abstract: RATIONALE: N-Alkylation of sulfonylbenzamides was reported recently to cause a dramatic and surprising change in electron ionization mass spectrometry (EIMS), leading to a closed-shell base peak. Only an incomplete, speculative mechanism was availabl ...

15. Fluorinated Copolymer Nanoparticles for Multimodal Imaging Applications
Topic: Drugs/Pharmaceuticals
Published: 2/18/2010
Authors: Mark M. Bailey, Christine M. Mahoney, Elodie Dempah, Jeffrey M. Davis, Matthew Becker, Supang Khondee, Eric J. Munson, Cory J. Berkland
Abstract: Nanomaterials have emerged as valuable tools in biomedical imaging techniques, such as magnetic resonance imaging (MRI), fluorescence, positron emission tomography (PET), and others. Some have been designed to serve as multimodal imaging agents, com ...

16. Guide for the Selection of Drug Detectors for Law Enforcement Applications
Topic: Drugs/Pharmaceuticals
Published: 8/1/2000
Author: Alim A Fatah
Abstract: This document surveys the field of contraband drug detection, with emphasis on different types of drug detection methods available and current commercial sources for detection equipment. The introduction includes background information on the proble ...

17. Membrane protein resistance of oligo(ethylene oxide) self-assembled monolayers
Topic: Drugs/Pharmaceuticals
Published: 7/31/2014
Authors: David J. Vanderah, Marlon L Walker, David Travis Gallagher, Ryan Vierling, Fay Crawshaw
Abstract: Spectroscopic ellipsometry was used to evaluate the resistance to protein adsorption (RPA) of self- assembled monolayers (SAMs) of HS(CH2)3O(CH2CH2O)6M and [HS(CH2)3CH]2O-(CH2CH2O)6M, where M = CH3 or H, on Au. The SAMs were exposed to fibrinogen ...

18. Microfluidic Remote Loading for Rapid Single-Step Liposomal Drug Preparation
Topic: Drugs/Pharmaceuticals
Published: 7/29/2014
Authors: Wyatt N Vreeland, Renee R Hood, Don L. DeVoe
Abstract: Here we report a microfluidic system that enables rapid and efficient remote loading of amphipathic drugs into nanoscale liposomes, combining liposome synthesis and remote drug loading in a continuous integrated process. Unlike established bulk m ...

19. Microfluidic preparation of liposomes to determine particle size influence on cellular uptake mechanisms
Topic: Drugs/Pharmaceuticals
Published: 10/3/2013
Authors: Wyatt N Vreeland, Abhay U Andar, Renee R Hood, Don L. DeVoe, Peter W Swaan
Abstract: Purpose: This study investigates the cellular uptake and trafficking of liposomes in Caco-2 cells, using vesicles with distinct average diameters ranging from 40 nm-276 nm. Liposomes were prepared by microfluidic hydrodynamic flow focusing, producing ...

20. Microfluidic-Enabled of Liposomes Elucidate Size-Dependent Transdermal Transport
Topic: Drugs/Pharmaceuticals
Published: 3/21/2014
Authors: Wyatt N Vreeland, Renee R Hood, Eric Kendall, Don L. DeVoe, Julia Finkel, Mariana Junqueira, Zenaide Quezado
Abstract: Microfluidic synthesis of small and nearly-monodisperse liposomes is used to investigate the size-dependent passive transdermal transport of nanoscale lipid vesicles. While large liposomes with diameters above 105 nm are found to be excluded from dee ...

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