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Topic Area: Drugs/Pharmaceuticals

Displaying records 21 to 30 of 43 records.
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21. A Streamlined Hydrolysis Procedure for the LC/MS/MS Analysis of Cocaine in Wastewater Samples
Topic: Drugs/Pharmaceuticals
Published: 1/2/2012
Authors: Katrice A Lippa, Kevin Bisceglia, A. Lynn Roberts
Abstract: We report a streamlined procedure for the routine analysis of cocaine in municipal wastewater. By adding NaOH (to 0.025 M) and incubating wastewater samples at 55 °C for two hours, cocaine and its principal metabolites are quantitatively converted i ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=903657

22. Recent Advances in Electrochemical Glyco-biosensing
Topic: Drugs/Pharmaceuticals
Published: 4/8/2011
Authors: Rebecca A Zangmeister, Germarie Sanchez-Pomales
Abstract: Biosensors based on electrochemical transduction mechanisms have recently made advances into the field of glycan analysis. These glyco-biosensor assays offer simple, rapid, sensitive and economical approaches to the measurement need for rapid glycan ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908197

23. A Comprehensive LC/MS/MS Method for the Determination of Cocaine and Other Drugs of Abuse in Municipal Wastewater: I. Quantification via SPE and Direct Injection
Topic: Drugs/Pharmaceuticals
Published: 9/24/2010
Authors: Katrice A Lippa, Michele M Schantz, A. Lynn Roberts, Kevin Bisceglia
Abstract: We present an isotopic dilution direct injection reverse phase liquid chromatography-tandem mass spectrometry (RPLC/MS/MS) method for the simultaneous determination of 23 drugs of abuse, drug metabolites, and human use markers in municipal wastewater ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=903656

24. Quantification of Drugs of Abuse in Municipal Wastewater via SPE and Direct Injection Liquid Chromatography Mass Spectrometry
Topic: Drugs/Pharmaceuticals
Published: 9/24/2010
Authors: Michele M Schantz, Katrice A Lippa, Kevin Bisceglia, A. Lynn Roberts
Abstract: We present an isotopic dilution direct injection reverse phase liquid chromatography-tandem mass spectrometry (RPLC/MS/MS) method for the simultaneous determination of 23 drugs of abuse, drug metabolites, and human use markers in municipal wastewater ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=904046

25. Fluorinated Copolymer Nanoparticles for Multimodal Imaging Applications
Topic: Drugs/Pharmaceuticals
Published: 2/18/2010
Authors: Mark M. Bailey, Christine M. Mahoney, Elodie Dempah, Jeffrey M Davis, Matthew Becker, Supang Khondee, Eric J. Munson, Cory J. Berkland
Abstract: Nanomaterials have emerged as valuable tools in biomedical imaging techniques, such as magnetic resonance imaging (MRI), fluorescence, positron emission tomography (PET), and others. Some have been designed to serve as multimodal imaging agents, com ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=902813

26. Isolation, Purification, and Full NMR Assignments of cyclopamine from Veratrum californicum
Topic: Drugs/Pharmaceuticals
Published: 6/24/2009
Authors: Daniel W Bearden, John E. Oatis, Pam Brunsfeld, James W. Rushing, Peter D. Moeller, Thomas N. Gallien, George W. Cooper
Abstract: The Hedgehog (Hh) signaling pathway is essential for embryogenesis and tissue homeostasis in the adult. However, it may also induce malignancies in a number of tissues when constitutively activated, and it also may have a role in other forms of nor ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=832291

27. Study of interaction of the cyclin-dependent kinase 5 with its activator, p25 and with the p25-derived inhibitor, CIP
Series: NIST Interagency/Internal Report (NISTIR)
Report Number: 7552
Topic: Drugs/Pharmaceuticals
Published: 1/15/2009
Authors: Antonio Cardone, Ram D Sriram, Wayne Albers, Harish C. Pant
Abstract: A high-affinity inhibitor protein called CIP, which can be produced by small truncations of p35, was earlier identified by Amin, Albers, and Pant. P35 is one of the physiological activators of cdk5, a member of the cyclin-dependent kinase family. The ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=901184

28. Solid State Chemistry of Proteins: II. The Correlation of Storage Stability of Freeze-Dried Human Growth Hormone (hGH) With Structure and Dynamics in the Glassy Solid
Topic: Drugs/Pharmaceuticals
Published: 12/1/2008
Authors: Michael Pikal, Daniel Rigsbee, Michael L Roy, Dawn Galreath, Karl J Kovach, Bingquan S. Wang, John F Carpenter, Marcus T Cicerone
Abstract: This research presents storage stability of human growth hormone, hGH, in a variety of lyophilized formulations, including systems of varying sugar:hGH weight ratios for both sucrose and trehalose. Stability was assessed at multiple time points durin ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=852769

29. Cold Chain Storage of Vaccines: A Brief Introduction to Thermometry
Series: NIST Interagency/Internal Report (NISTIR)
Topic: Drugs/Pharmaceuticals
Published: 9/1/2008
Author: Dean C Ripple
Abstract: To maintain the efficacy of vaccines requires maintaining the storage temperature within well-defined limits; vaccine failure due to improper storage results in large direct and indirect public health costs. In this presentation, I give a brief intro ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=832372

30. Quantitation of HER2 and Telomerase Biomarkers in Solid Tumors with IgY Antibodies and Nanocrystal Detection
Topic: Drugs/Pharmaceuticals
Published: 5/15/2008
Authors: Yan Xiao, X Gao, G Gannot, M Emmert-Buck, S Srivastava, Paul D Wagner, Michael D. Amos, Peter E. Dr. Barker
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=901234



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