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Displaying records 11 to 20 of 66 records.
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11. Effect of 3D Scaffold Structure on Osteogenic Differentiation of Human Bone Marrow Stromal Cells
Topic: Biomaterials
Published: 4/24/2011
Authors: Carl George Simon Jr., Girish Kumar, Marian F Young
Abstract: Structural properties of polymeric scaffolds for tissue engineering play a key role in directing osteogenesis. These properties depend on the chemical nature and the fabrication process of biomaterial. There are many protocols for fabricating scaff ...

12. Effect of Polymer Degree of Conversion on Streptococcus mutans Biofilms
Topic: Biomaterials
Published: 10/5/2012
Authors: Alison M. Kraigsley, Kathy Tang, John A. Howarter, Katrice A Lippa, Sheng Lin-Gibson, Nancy J Lin
Abstract: The effects of key material properties of polymeric composite restorations on cariogenic oral biofilms are needed to provide insight into the materials‰ role in recurrent caries. The objective of this study was to quantify the effects of degree of co ...

13. Effect of offset values of solid freeform fabricated PCL/ß-TCP scaffolds on mechanical properties and cellular activities in bone tissue regeneration
Topic: Biomaterials
Published: 11/1/2012
Authors: Carl George Simon Jr., GeunHyung Kim, MyungGu Yo
Abstract: Microstructures of biomedical scaffolds can greatly affect cellular activities in tissue regeneration. In particular, scaffolds used in bone tissue regeneration should have several microstructural characteristics, including high porosity, appropriate ...

14. Electrochemical Study of Chitosan Films Deposited on Gold Electrodes
Topic: Biomaterials
Published: 7/28/2006
Authors: Rebecca A Zangmeister, J J Park, G W Rubloff, Michael J Tarlov
Abstract: We report the electrochemical characterization of chitosan films deposited on gold electrodes. Cyclic voltammetry was used to characterize the deposition and electroactivity of chitosan coated gold electrodes. Chitosan films were found to deposit a ...

15. Facile Fabrication of "Dual Click" One- and Two-Dimensional Orthogonal Peptide Concentration Gradients
Topic: Biomaterials
Published: 1/21/2013
Authors: Yanrui Ma, Jukuan Zheng, Emily F. Amond, Christopher M Stafford, Matthew L Becker
Abstract: Peptides, proteins and extracellular matrix act in concert to influence cellular function at the biotic-synthetic interface. However identifying the individual and synergistic contributions of the various combinations and concentration regimes is e ...

16. Fine-tuning of polymeric resins and their interfaces with amorphous calcium phosphate. A strategy for designing effective remineralizing dental composites
Topic: Biomaterials
Published: 9/29/2010
Authors: Joseph M Antonucci, Drago Skrtic
Abstract: For over a decade our group has been designing, preparing and evaluating bioactive, remineralizing composites based on amorphous calcium phosphate (ACP) fillers embedded in polymerized methacrylate resin matrices. In these studies a major focus has b ...

17. Freeform Fabricated Scaffolds with Roughened Struts that Enhance both Stem Cell Proliferation and Differentiation by Controlling Cell Shape
Topic: Biomaterials
Published: 3/1/2012
Authors: Girish Kumar, Carl George Simon Jr., Michael S. (Michael Stephan) Waters, Tanya M. Farooque, Marian F Young
Abstract: We demonstrate that imparting freeform fabricated (FFF) scaffolds with surface roughness on their struts enhances osteogenic differentiation of primary human bone marrow stromal cells (hBMSCs) by controlling cell shape. Previous work showed that hBM ...

Topic: Biomaterials
Published: 10/28/2012
Authors: Conni Hanke, Petra S. Dittrich, Darwin R Reyes-Hernandez
Abstract: A cell co-culture was generated on opposite sides of a permeable polyester membrane (PET) membrane by combining dielectrophoretic (DEP) and electrostatic forces to hold cells against gravity in a multilayer microfluidic device (Figure 1). HepG2 cell ...

19. Gas-Foamed Scaffold Gradients for Combinatorial Screening in 3D
Topic: Biomaterials
Published: 5/1/2012
Authors: Carl George Simon Jr., Kaushik Chatterjee, Alison M. Kraigsley, Joachim Kohn, Durgadas Bolikal
Abstract: Current methods for screening cell-material interactions typically utilize two-dimensional (2D) culture format where cells are cultured on flat surfaces. However, there is a need for combinatorial and high-throughput screening methods to systematica ...

20. Gradient Nanofiber Scaffold Libraries for Rapid Screening of Cell-Material Interactions
Topic: Biomaterials
Published: 12/1/2009
Authors: Carl George Simon Jr., Murugan Ramalingam, Marian F Young, Vinoy Thomas
Abstract: Scaffolds play a key role in tissue engineering wherein they provide structural support for cells to adhere, grow and guide them to synthesize tissue. Scaffolds made of multiple biomaterials are typically required to mimic the three-dimensional (3D) ...

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