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You searched on: Topic Area: Advanced Materials

Displaying records 31 to 40 of 71 records.
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31. Gas-Foamed Scaffold Gradients for Combinatorial Screening in 3D
Topic: Advanced Materials
Published: 5/1/2012
Authors: Carl George Simon Jr., Kaushik Chatterjee, Alison M. Kraigsley, Joachim Kohn, Durgadas Bolikal
Abstract: Current methods for screening cell-material interactions typically utilize two-dimensional (2D) culture format where cells are cultured on flat surfaces. However, there is a need for combinatorial and high-throughput screening methods to systematica ...

32. Osteoblast Response to Serum Protein Adsorption in 3D Polymer Scaffolds
Topic: Advanced Materials
Published: 5/1/2012
Authors: Carl George Simon Jr., Girish Kumar, Kaushik Chatterjee, Stevephen Hung
Abstract: Protein adsorption is known to direct biological response to biomaterials and is important in determining cellular response in tissue scaffolds. In this study we investigated the effect of adsorbed serum proteins on cell attachment and proliferation ...

33. Nano-Apatitic Composite Scaffolds for Stem Cell Delivery and Bone Tissue Engineering
Topic: Advanced Materials
Published: 4/15/2012
Authors: Hockin H. K. Xu, Carl George Simon Jr.
Abstract: The need for bone defect repair and regeneration arises from trauma, disease, congenital deformity, and tumor resection. Bone fracture occurs to seven million people each year in the United States, and musculoskeletal conditions cost $215 billion ann ...

34. Freeform Fabricated Scaffolds with Roughened Struts that Enhance both Stem Cell Proliferation and Differentiation by Controlling Cell Shape
Topic: Advanced Materials
Published: 3/1/2012
Authors: Girish Kumar, Carl George Simon Jr., Michael S. (Michael Stephan) Waters, Tanya M. Farooque, Marian F Young
Abstract: We demonstrate that imparting freeform fabricated (FFF) scaffolds with surface roughness on their struts enhances osteogenic differentiation of primary human bone marrow stromal cells (hBMSCs) by controlling cell shape. Previous work showed that hBM ...

35. Control of Molecular Mass Distributions in Enzymatic Lactone Polymerizations
Topic: Advanced Materials
Published: 2/2/2012
Authors: Santanu S. Kundu, Peter M. Johnson, Kathryn L Beers
Abstract: Using a model developed for the enzyme catalyzed polymerization and degradation of poly(caprolactone), we illustrate methods and the kinetic mechanisms necessary to improve molecular mass distributions by manipulating equilibrium reactions in the kin ...

36. Automated Data Processing and Quantification in Polymer Mass Spectrometry
Topic: Advanced Materials
Published: 12/1/2011
Authors: Till Gruendling, Christopher Barner-Kowollik, William E Wallace III, Charles Martin Guttman, Anthony J Kearsley
Abstract: An overview is given of some new techniques in quantitative composition and molecular mass distribution measurement of synthetic polymers by mass spectrometry. New concepts in data analysis, including peak picking and integration, are also described ...

37. Molecular Layer-by-Layer Deposition of Highly Crosslinked Polyamide Membranes for Reverse Osmosis Applications
Topic: Advanced Materials
Published: 11/19/2011
Authors: Peter M. Johnson, Joonsung (Joonsung) Yoon, Jennifer Y. Kelly, John A. Howarter, Christopher M Stafford
Abstract: In membranes for reverse osmosis and nanofiltration, the discriminating layers consist of an interfacially polymerized polyamide film on a porous support. For reverse osmosis membranes, the dominant commercial interfacial film is a crosslinked netwo ...

38. Self-Repairing Complex Helical Columns Generated via Kinetically Controlled Self-Assembly of Dendronized Perylene Bisimides
Topic: Advanced Materials
Published: 11/16/2011
Authors: Virgil Percec, Steven D Hudson, Mihai Peterca, Pawaret Leowanawat, Emad Aqad, Robert Graf, Hans -W Spiess, Xiangbing Zeng, Goran Ungar, Paul A Heiney
Abstract: The dendronized perylene 3,4:9,10-tetracarboxylic acid bisimide (PBI) (3,4,5)12G1-3-PBI was recently shown to self-assemble in a complex helical column containing tetramers of PBI as the basic repeat unit. The tetramers contain a pair of two molecule ...

39. Synthesis of Polymer-derived Ceramic Si(B)CN-Carbon Nanotube Composite by Microwave Induced Interfacial Polarization
Topic: Advanced Materials
Published: 10/12/2011
Authors: Romil Bhandavat, William Kuhn, Elisabeth Mansfield, John H Lehman, Gurpreet Singh
Abstract: We demonstrate synthesis of a polymer-derived ceramic (PDC)-multiwall carbon nanotube (MWCNT) composite using microwave irradiation at 2.45 GHz. The process takes about 10 minutes of microwave irradiation for the polymer to ceramic conversion. The su ...

40. Morphological Changes Driven by Nanofibrous Scaffolds Induce Marrow Stromal Cell Osteogenesis
Topic: Advanced Materials
Published: 10/11/2011
Authors: Carl George Simon Jr., Kaushik Chatterjee, Christopher K. Tison, Girish Kumar, Patrick S Pine, Marc L Salit, Jennifer H McDaniel, Marian F Young
Abstract: Cells are sensitive to tissue scaffold architecture and these cell-material interactions drive cell functions critical in tissue regeneration. Results presented here demonstrate that nanofiber scaffolds force primary human bone marrow stromal cells ...

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