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Author: Gregory Cooksey
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1. A robust diffusion-based gradient generator for dynamic cell assays.
Francisco Javier Atencia, Gregory A Cooksey, Laurie E Locascio
This manuscript describes a new method to generate purely diffusive chemical gradients that can be modified in time. The device
is simple in its design and easy to use, which makes it amenable to study biological processes that involve static or dy ...
2. Reproducibility and Robustness of a Real-Time Microfluidic Cell Toxicity Assay
Gregory A Cooksey, John T Elliott, Anne L Plant
Numerous opportunities exist to apply microfluidic technology to high-throughput and high-content
cell-based assays. However, maximizing the value of these assays for drug discovery, screening or
toxicity evaluation, for example, will require va ...
3. Magnetic connectors for microfluidic applications
Francisco Javier Atencia, Gregory A Cooksey, Andreas Jahn, Justin M Zook, Wyatt N Vreeland, Laurie E Locascio
We present a new type of connector based on a simple idea: using a ring magnet on one side of the microfluidic chip and a disc magnet on the other side to provide the interfacial force necessary to provide a sealed connection between tubing or needle ...
4. A vacuum manifold for rapid world-to-chip connectivity of complex PDMS microdevices
Gregory A Cooksey, Anne L Plant, Francisco Javier Atencia
The lack of simple interfaces for microfluidic devices with a large number of inlets significantly limits production and utilization of these devices. In this paper, we describe the fabrication of a reusable manifold that provides rapid world-to-chi ...