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You searched on: Author: Michael Halter

Displaying records 1 to 10 of 21 records.
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1. Dimensional Metrology of Lab on a Chip Internal Structures: a Comparison of Optical Coherence Tomography with Coherence Fluorescence Microscopy
Published: 4/8/2015
Authors: Darwin R Reyes-Hernandez, Michael W Halter, Jeeseong Hwang
Abstract: The characterization of internal structures in a polymeric device, specifically of a final product, will require a different set of metrology techniques than those traditionally use in the characterization of microelectronic devices. OCT is relati ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912533

2. High Resolution Surface Plasmon Resonance Imaging for Single Cells
Published: 12/1/2014
Authors: Alexander W Peterson, Michael W Halter, Alessandro Tona, Anne L Plant
Abstract: Background Surface plasmon resonance imaging (SPRI) is a label-free technique that can image refractive index changes at an interface. We have previously shown that SPRI can be used to study the dynamics of cell-substratum interactions. However, c ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914643

3. Nonparametric Estimates of Drift and Diffusion Profiles via Fokker-Planck Algebra
Published: 10/13/2014
Authors: Steven P Lund, Michael W Halter, Joseph Bunton Hubbard
Abstract: Diffusion processes superimposed upon deterministic motion play a key role in understanding and controlling the transport of matter, energy, momentum, and even information in physics, chemistry, material science, biology, and communications techn ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915954

4. Automated Ranking of Stem Cell Colonies by Translating Biological Rules to Computational Models
Published: 9/20/2014
Authors: Adele P Peskin, Steven P Lund, YaShian Li-Baboud, Michael W Halter, Anne L Plant, Peter Bajcsy
Abstract: This paper addresses the problem of automating an image ranking process for stem cell colonies. We automate the manual process in a novel way: instead of fitting off-the-shelf image features and colony ranks to prediction models, we define a new feat ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915931

5. Performance Benchmarking and Intensity Calibration of a Widefield Fluorescence Microscope Using Fluorescent Glass
Published: 8/11/2014
Authors: Michael W Halter, Elianna Bier, Paul C DeRose, Gregory A Cooksey, Steven J Choquette, Anne L Plant, John T Elliott
Abstract: Widefield fluorescence microscopy is a highly used tool for visually assessing biological samples and for quantifying cell responses. Despite its widespread use in high content analysis and other screening applications, few published methods exist f ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915188

6. Testing Equality of Cell Populations Based on Shape and Geodesic Distance
Published: 12/3/2013
Authors: Robert Charles Hagwood, Javier Bernal, Michael W Halter, John T Elliott
Abstract: Image cytometry has emerged as a valuable in-vitro screening tool and advances in automated microscopy have made it possible to readily analyze large cellular populations of image data. A statistical procedure to study homogeneity of such data ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=911573

7. Optical Coherence Tomography for Dimensional Metrology of Lab-on-a-chip devices
Published: 10/27/2013
Authors: Darwin R Reyes-Hernandez, Michael W Halter, Jeeseong Hwang
Abstract: Here we present a new metrology tool for the determination of the dimensions of channels from final product Lab-on-a-chip devices. Using Optical Coherence Tomography (OCT) areas of up to 12 mm x 12 mm can be imaged in less than 1 second, without the ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914314

8. Measurement Uncertainty in Cell Image Segmentation Data Analysis
Series: NIST Interagency/Internal Report (NISTIR)
Report Number: 7954
Published: 8/13/2013
Authors: Jin Chu Wu, Michael W Halter, Raghu N Kacker, John T Elliott, Anne L Plant
Abstract: Cell image segmentation is a part of quantitative studies regarding cell movement and cell behavior, and it plays a critical role in molecular biology and cellular biochemistry. Therefore, it is fundamentally important to evaluate the performance ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914171

9. Boltzmann's H-Function and Diffusion Processes
Published: 5/15/2013
Authors: Steven P Lund, Joseph Bunton Hubbard, Michael W Halter
Abstract: There exists a generalization of Boltzmann's $H$-function that allows for non-uniformly populated stationary states which may exist far from thermodynamic equilibrium. Here we describe a method for obtaining a generalized or collective diffusion coef ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913439

10. Metrology for Lab-on-a-Chip Final-Product Devices
Published: 5/12/2013
Authors: Darwin R Reyes-Hernandez, Michael W Halter, Jeeseong Hwang
Abstract: New metrology tools to measure the critical parameters of internal structures in lab on a chip devices are greatly needed in order to develop standard tests for this technology. Here we present a method that combines a custom made optical coherence ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913496



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