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Author: Karen Phinney

Displaying records 1 to 10 of 51 records.
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1. Quantitative bottom-up proteomics depends on digestion conditions
Published: 12/2/2013
Authors: Mark S Lowenthal, Yuxue Liang, Karen W Phinney, Stephen E Stein
Abstract: Accurate quantification is a fundamental requirement in the fields of proteomics and biomarker discovery, and for clinical diagnostic assays. To demonstrate the extent of quantitative variability in measurable peptide concentrations due to differenc ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914393

2. Development of a Standard Reference Material for Metabolomics Research
Published: 11/4/2013
Authors: Karen W Phinney, Guillaume Ballihaut, Mary Bedner, Johanna Camara, Steven J Christopher, William C Davis, Nathan G. Dodder, Brian E Lang, Stephen E Long, Mark S Lowenthal, Elizabeth A. McGaw, Karen E Murphy, Bryant C Nelson, Jocelyn L. Prendergast, Jessica L Reiner, Catherine A Rimmer, Lane C Sander, Michele M Schantz, Katherine E Sharpless, Lorna Tregoning Sniegoski, Susan Shu Cheng Tai, Jeanice M Brown Thomas, Thomas W Vetter, Michael James Welch, Stephen A Wise, Laura J Wood, William F Guthrie, Robert Charles Hagwood, Stefan D Leigh, James H Yen, Nien F Zhang, Madhu Chaurhary-Webb, Huiping Chen, Bridgette Haynes, Donna J LaVoie, Leslie F McCoy, Shahzad S Momin, Neelima Paladugula, Elizabeth C Pendergrast, Christine M Pfeiffer, Carissa D Powers, Zia Fazili-Qari, Daniel Rabinowitz, Michael E Rybak, Rosemary L Schleicher, Mary Xu, Mindy Zhang, Arthur L Castle, Brandi S Benford, Gauthier Eppe
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912559

3. Metabolite Profiling of a NIST Standard Reference Material for Human Plasma (SRM 1950) ‹ GC/MS, LC/MS, NMR and Clinical Laboratory Analyses, Libraries and Web-based resources
Published: 10/22/2013
Authors: Yamil Simon, Mark S Lowenthal, Lisa Ervin Kilpatrick, Maureen L Sampson, Kelly H Telu, Paul A Rudnick, William Gary Mallard, Daniel W Bearden, Tracey Beth Schock Schock, Dmitrii V Tchekhovskoi, Niksa Blonder, Xinjian Yan, Yuxue Liang, Yufang Zheng, William E Wallace III, Pedatsur Neta, Karen W Phinney, Alan T. Remaley, Stephen E Stein
Abstract: Recent progress in metabolomics and the development of increasingly sensitive analytical techniques have renewed interest in global profiling, i.e., semi-quantitative monitoring of all chemical constituents of biological fluids. In this work, we have ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913835

4. Quantification of transferrin in human serum using both QconCAT and synthetic internal standards
Published: 9/27/2013
Authors: Tyler A. (Tyler) Zimmerman, Meiyao M. Wang, Mark S Lowenthal, Illarion V Turko, Karen W Phinney
Abstract: Transferrin, an iron transport protein, is a clinically-important biomarker in diseases such as iron-deficiency anemia. Current diagnostic methods for transferrin levels lack quantitative accuracy, suggesting the need for alternative approaches ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914041

5. The Development and Implementation of Quality Assurance Programs to Support Nutritional Measurements
Published: 5/24/2013
Authors: Lane C Sander, Mary Bedner, David Lee Duewer, Katrice A Lippa, Melissa Meaney Phillips, Karen W Phinney, Catherine A Rimmer, Michele M Schantz, Katherine E Sharpless, Susan Shu Cheng Tai, Jeanice M Brown Thomas, Stephen A Wise, Laura J Wood, J. M. Betz, Paul M Coates
Abstract: The National Institute of Standards and Technology administers quality assurance programs devoted to improving measurements of nutrients and related metabolites in foods, dietary supplements, and serum and plasma samples. These programs have been de ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912409

6. Universal Proteolysis and MSn for N- and O- Glycan Branching Analysis
Published: 4/20/2013
Authors: John E Schiel, Karen W Phinney, Nicholas J Smith
Abstract: The continually growing list of critical glycosylation-related processes has made analytical methodology for detailed glycan characterization an area of increasing interest. Glycosylation is a post translational modification of unsurpassed comple ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912398

7. Determination of fortified and endogenous folates in food-based Standard Reference Materials by liquid chromatography-tandem mass spectrometry
Published: 1/26/2013
Authors: Johanna Camara, Mark S Lowenthal, Karen W Phinney
Abstract: The National Institute of Standards and Technology (NIST) is developing a wide variety of Standard Reference Materials (SRMs) to support measurements of vitamins and other nutrients in foods. Previously, NIST has provided SRMs with values assigned f ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912489

8. Characterizing Vaccinium berry Standard Reference Materials using NIST Mass Spectral Libraries
Published: 1/6/2013
Authors: Mark S Lowenthal, Nirina Rabe Andriamaharavo, Stephen E Stein, Karen W Phinney
Abstract: A gas chromatography-mass spectrometry-based (GC-MS) method was developed for qualitative characterization of metabolites found in Vaccinium-fruit (berry) dietary supplement Standard Reference Materials (SRMs). Definitive identifications are pro ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912593

9. Quantifying CD4 Receptor Density on Human T Lymphocytes Using Multiple Reaction Monitoring Mass Spectrometry
Published: 1/3/2013
Authors: Meiyao M. Wang, Hua-Jun He, Illarion V Turko, Karen W Phinney, Lili Wang
Abstract: CD4 is an important glycoprotein containing a transmembrane portion and a short intracellular tail. It locates on the surface of various types of immune cells and performs critical role in multiple cellular functions such as signal amplification and ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912487

10. Developing qualitative LC-MS methods for characterization of Vaccinium berry Standard Reference Materials
Published: 9/2/2012
Authors: Mark S Lowenthal, Melissa Meaney Phillips, Catherine A Rimmer, Paul A Rudnick, Yamil Simon, Stephen E Stein, Karen W Phinney
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=911317



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