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NIST Awards Nearly $3 Million to Small Businesses to Advance Semiconductor Manufacturing, Drug Development and More

  • Fifteen small businesses in nine states will advance new technologies under NIST’s Small Business Innovation Research (SBIR) Program.
  • Awardees receive up to $100,000 for Phase I projects and up to $400,000 for Phase II projects.
Micrograph shows woven fibers in diagonal pattern.
This colorized micrograph reveals thinner (yellow) and thicker (blue) regions of a 100% polyester fabric used in face masks. The NIST SBIR program supports research at small businesses such as developing a method to measure the effectiveness of face masks and respirators in real-world conditions.
Credit: NIST

GAITHERSBURG, Md. — The U.S. Department of Commerce’s National Institute of Standards and Technology (NIST) has awarded nearly $3 million to 15 small businesses in nine states under the Small Business Innovation Research (SBIR) Program. The funding will go to research and development and commercialization projects to support a variety of technology-based programs such as advances in semiconductors, drug development and flexible electronics manufacturing.

The competitively selected proposals were submitted in response to a call for innovative products addressing specific technical needs in NIST areas of research including advanced communications, cybersecurity and privacy, health and biological systems measurements, advanced manufacturing and more.

SBIR Phase I awardees will receive up to $100,000 to establish the merit, feasibility and commercial potential of the proposed research and development. After completing their Phase I projects, awardees are eligible to apply for Phase II funding of up to $400,000 to continue their efforts. Phase III relies on non-SBIR funds for technology commercialization.

2023 Phase I SBIR Awardees

Actoprobe LLC (Albuquerque, New Mexico) $99,909
Scanning Probe Microscopy with Active Optical Probes: A Novel Approach to Measurements and Nanomanufacturing — a novel class of near-field optical probes that will allow precise optical characterization on the single-molecule and even submolecular scale, with applications in biotechnology, 3D printing and more.

Applied Research Transformation (Durham, North Carolina) $100,000
Sentinel 4.0TM: Measurement and Control System for 3DCP Interlayer Bond Strength — a commercial system for measuring and controlling the quality of bond strength in 3D-printed concrete under multiple environmental conditions.

ChemCubed LLC (Stony Brook, New York) $99,998
Printable Dielectric for Flexible Hybrid Electronics — a stretchable dielectric ink for printing flexible electronic circuits that could be used in wearable sensors, ultra-lightweight and flexible photovoltaics and other applications where flexibility is needed.

Exabyte Inc. (Walnut Creek, California) $99,895
Developing Data Standards for Accelerated Digital R&D of Semiconductor Materials from Nanoscale — data standards for accelerated research and development of semiconductor materials at the nanoscale.

Framergy Inc. (College Station, Texas) $100,000
A Novel Advanced Manufacturing Pathway for Direct Incorporation of Metal-Organic Frameworks in Polymeric Sponges — polymer composites that incorporate metal-organic frameworks (MOFs), for potential use as air and water filters for the treatment of harmful chemicals. 

ITA International LLC (Newport News, Virginia) $99,292
Method for Quantifying Fitted Filtration Efficiency of Face Mask and Respirator Products — research leading up to development of a novel Fitted Filtration Efficiency (FFE) protocol to assess mask/respirator effectiveness for as-worn conditions.

QuantTera LLC (Tempe, Arizona) $99,977
Heterogeneous Millimeter-Wave Gallium Nitride Heterojunction Bipolar Transistor — development of high-performance radio frequency power amplifiers for use in wireless network communications systems.

Rownd Inc. (Raleigh, North Carolina) $96,644
Accelerating Adoption of Anti-Phishing Authentication Methods — analysis of the costs of moving from password-based to passwordless systems, understanding the various passwordless options and their merits, and recognizing the risks of maintaining passwordless methods to increase phishing-resistant systems. 

SygnaMap (San Antonio, Texas) $100,000
Metabolite Reference Standards to Normalize Spatial Metabolomics Across Tissue Sections — an innovative computational platform to analyze data from spatial metabolomics — an emerging field of bioanalytical chemistry that aims to observe cellular biology with the greatest detail possible — for use in drug development.

Xmark Labs LLC (Barrington, Rhode Island) $100,000
Feasibility and Proof of Concept of a Dense, Low-Cost Network of Sensors Driving Intelligent Building Agents for Air Quality and Energy Control — establish the feasibility and proof of concept of a networked, affordable environmental sensor to enhance energy control and air quality regulation for commercial buildings.

2023 Phase II SBIR Awardees

Criticality Sciences (Alexandria, Virginia) $400,000
Network Resilience to Cascading Failure — validation of data inputs and outputs and the development of methods to use metrics to support resilience investment and financing for critical infrastructure such as water and power utilities.

InfraTrac Inc. (Silver Spring, Maryland) $400,000
Analytical Quality Management for 3D-Printed Small Molecule Drugs — predictive modeling and near-infrared spectroscopy for 3D drug printing to enable customized doses, child-friendly formulations and easy-to-remember combination polypills.

Interlink Electronics Inc. (Irvine, California) $398,622
Materials for Gravure Printing of Chemical Gas Sensors — development of manufacturing techniques such as roll-to-roll printing to enable mass production of electrochemical gas sensors, as well as suitable chemistries for large-scale printed sensors and testing methods.

Julia Jean LLC (Irvine, California) $400,000
On-Chip Cold Cathode Electron Sources for X-Ray Generation and Imaging: Advancing a NIST-Patented Technology — a project to identify and compare the variables in a new lithography procedure for the best process for manufacturing the technology at scale. 

Tiami LLC (Elk Grove, California) $399,979
Digital TV-Based Positioning for First Responder Tracking in GPS-Denied Environments — prototyping of a portable digital television-based positioning receiver and demonstration of the use of over-the-air Advanced Television Systems Committee (ATSC) 3.0 broadcast transmissions to improve indoor positioning and navigation where GPS coverage is not available. 

Released December 19, 2023