The Biomaterials Group develops methods and reference materials for characterizing interactions of materials and biological systems. This work is in support of biotechnology – related research areas and industries, both new and established. Our current focus areas cover dental materials, biopharmaceutics, and regenerative medicine. A major focus of the group is development of analytical methods for extracting quantitative and statistically significant information from systems of interest in a non-invasive or minimally-invasive way. These efforts are leveraged by research carried out collaboratively with Universities and other Federal Agencies to improve important aspects of health care diagnostics and therapeutics, and to improve performance of materials used in biotechnological industries. The group's activities are carried out in four project areas.
3D Tissue Scaffolds—Our goal is to develop advanced measurement tools and standards for measuring polymer scaffold properties and their impact on biological response.
Broadband CARS Microscopy—The traditional chemical labeling used in optical microscopy can alter cells and materials, thus impeding determination of their true structure, function and response. We are developing broadband …
Dental Materials Project—Our goal is to provide measurement methods and reference materials to facilitate the rational design of polymeric dental materials, thus enabling improvements in their clinical performance. …
Bioimaging—Our goal is to develop methods and materials for imaging-based characterization of molecular signatures that occur during cellular proliferation, differentiation and internalization, in order to …
Protein Preservation—Our goal is to address critical measurement issues that exist regarding chemical and physical stability of biomacromolecules (proteins and DNA) in hydrophilic, hydrogen-bonding glasses such as …
Material Measurement Laboratory (MML)
Biosystems and Biomaterials Division
100 Bureau Drive, M/S 8543