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Publication Citation: A New NIST Primary Standardization of 18F

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Author(s): Ryan P. Fitzgerald; Brian E. Zimmerman; Denis E. Bergeron; Jeffrey T. Cessna; Leticia S. Pibida; Denise S. Moreira;
Title: A New NIST Primary Standardization of 18F
Published: February 01, 2014
Abstract: A new primary standardization of 18F by NIST is reported. The standard is based on live-timed beta- gamma anticoincidence counting with confirmatory measurements by three other methods: (i) liquid scintillation (LS) counting using CIEMAT/NIST 3H efficiency tracing; (ii) triple-to-double coincidence ratio (TDCR) counting; and (iii) NaI integral counting and HPGe γ-ray spectrometry. The results are reported as calibration factors for NIST-maintained ionization chambers (including some ,dose calibratorsŠ). The LS-based methods reveal evidence for cocktail instability for one LS cocktail. Using an ionization chamber to link this work with previous NIST results, the new value differs from the previous reports by about 4 %, but appears to be in good agreement with the Key Comparison Reference Value (KCRV) of 2005.
Citation: Applied Radiation and Isotopes
Volume: 85
Pages: pp. 77 - 84
Keywords: fluorine-18; 18F; F-18; primary standardization; anticoincidence; TDCR; CIEMAT/NIST; ionization chamber; dose calibrator
Research Areas: Radiation Physics
DOI: http://dx.doi.org/10.1016/j.apradiso.2013.11.116  (Note: May link to a non-U.S. Government webpage)