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Publication Citation: Simple device for rare cell capture from whole blood

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Author(s): Jason G. Kralj; Samuel P. Forry; Matthew S. Munson; Thomas P. Forbes; Chandamany Arya; Lynn Sorbara; Alessandro Tona; Sudhir Srivastava;
Title: Simple device for rare cell capture from whole blood
Published: September 26, 2012
Abstract: We have developed a system to isolate rare cells from whole blood using commercially available components and simple microfluidics that can provide biologists with the capabilities of the monolithic devices. We characterized the capture of MCF-7 cells spiked into whole human blood to demonstrate that enrichment and even enumeration studies are possible, and enabling engineers and biologists access to this technology.
Citation: Lab on A Chip
Keywords: microfluidics; rare cell capture; circulating tumor cells; whole blood assay
Research Areas: Microfluidics, Diagnostics