| Author(s): |
Zachary H. Levine; Adam L. Pintar; John G. Hagedorn; Charles D. Fenimore; Claus P. Heussel; |
| Title: |
Uncertainty in RECIST as a measure of volume for lung nodules and liver malignoma |
| Published: |
April 27, 2012 |
| Abstract: |
The authors investigate the extent to which the RESPONSE Evaluation Criateria in Solid Tumors (RECIST) can predict tumor volumes and changes in volume using clinical data. The data presented are a reanalysis of data acquired in other studies, including the public database from the Lung Image Database Consortium (LID) and from a study of liver malignoma. The principal conclusion is that a given RECIST diameter predicts volume to a factor of 17 or 10 respectively with 95 % confidence and that changes in volume are predicted only a little better: to within a factor of 8 for the liver data. Additionally, we show the RECIST threshold of 10 mm to follow a nodule corresponds to a transition zone of a factor fo 10 in volume for the nodules in the LIDC database. |
| Citation: |
Medical Physics |
| Volume: |
39 |
| Issue: |
5 |
| Pages: |
pp. 2628 - 2637 |
| Keywords: |
RECIST ; LIDC ; nodule ; volumetrics |
| Research Areas: |
Medical Devices, Bioscience & Health |
| PDF version: |
 Click here to retrieve PDF version of paper (1MB) |
