| Author(s): |
Matthew T. Hunley; Atul Bhangale; Santanu S. Kundu; Peter M. Johnson; Michael S. Waters; Richard Gross; Kathryn L. Beers; |
| Title: |
In situ monitoring of enzyme-catalyzed (co)polymerizations by Raman spectroscopy |
| Published: |
November 10, 2011 |
| Abstract: |
In situ, fiber optic-based Raman spectroscopy provided real time monitoring of enzyme-catalyzed ring-opening homo- and copolymerizations of ε-caprolactone (ε-CL) and δ-valerolactone (δ-VL). A custom designed reactor equipped with in situ fiber optic probe was used to measure monomer conversion as a function of time. The results from the in situ technique were in good agreement with those determined by offline 1H NMR analysis. Monomer reactivity ratios for the lipase-catalyzed copolymerization of ε-CL and δ-VL were estimated using the Kelen-Tudos method as rε-CL = 0.38 and rδ-VL = 0.29. |
| Citation: |
Polymer Chemistry |
| Keywords: |
Raman spectroscopy, enzyme-catalyzed polymerization, ring-opening polymerization, copolymerization, reactivity ratios |
| Research Areas: |
Characterization, Polymers, Raman |
| PDF version: |
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