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Publication Citation: Effect of 3D Scaffold Structure on Osteogenic Differentiation of Human Bone Marrow Stromal Cells

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Author(s): Carl G. Simon Jr; Girish Kumar; Marian F. Young;
Title: Effect of 3D Scaffold Structure on Osteogenic Differentiation of Human Bone Marrow Stromal Cells
Published: April 24, 2011
Abstract: Structural properties of polymeric scaffolds for tissue engineering play a key role in directing osteogenesis. These properties depend on the chemical nature and the fabrication process of biomaterial. There are many protocols for fabricating scaffolds for bone tissue engineering applications which afford control over scaffold topography. In addition, much work has demonstrated that cell differentiation is sensitive to topography at sizes ranging from nano- to micro- to macroscale. Thus, we have investigated the effect of different scaffold topographies on differentiation of human bone marrow stromal cells (hBMSCs).
Conference: Society for Biomaterials
Pages: 1 pp.
Location: Orlando, FL
Dates: April 13-16, 2011
Keywords: polymer scaffold; stem cell; osteogenesis; nanofiber;
Research Areas: Polymers, Polymers, Materials Science, Biomaterials, Biomaterials, Biomaterials, Bioscience & Health, Advanced Materials