| Author(s): |
William E. Wallace III; Kathleen M. Flynn; Charles M. Guttman; David L. VanderHart; Vivek M. Prabhu; Anuja De Silva; Nelson Felix; Christopher K. Ober; |
| Title: |
Quantitative Measurement of the Polydispersity in the Extent of Functionalization of Glass Forming Resorcinarenes |
| Published: |
May 01, 2009 |
| Abstract: |
The polydispersity in the degree of functionalization for two calix[4]resorcinarenes was determined by measuring their molecular mass distribution with matrix-assisted laser desorption/ionization time of flight mass spectrometry. A mathematical method for polydisperse materials is described that creates a calibration curve to correct the ion intensities in the mass spectrum to give a more reliable molecular mass distribution. Correction is required due to various sample preparation and instrumental effects that may produce a systematic bias on the number of oligomers measured. This method employs gravimetric mixtures of analytes with different degrees of functionalization. One calix[4]resorcinarene was found to give accurate molecular mass distributions with little correction, while another having a very similar molecular structure was found to exhibit strong over counting of oligomers with a high degree of functionalization. |
| Citation: |
Rapid Communications in Mass Spectrometry |
| Volume: |
23 |
| Pages: |
pp. 1957 - 1962 |
| Keywords: |
glass; mass spectrometry; photolithography; |
| Research Areas: |
Polymers |
| PDF version: |
 Click here to retrieve PDF version of paper (681KB) |
