| Author(s): |
Vincent A. Hackley; Jeffrey D. Clogston; |
| Title: |
Measuring the Hydrodynamic Size of Nanoparticles in Aqueous Media Using Batch-Mode Dynamic Light Scattering |
| Published: |
January 01, 2011 |
| Abstract: |
Particle size characterization is of particular importance to nanomedicine as “nano” is a dimensional definition, and the size similarity of nanoparticles to biological moieties is believed to impart many of their unique medical properties. Here we present a method for sample preparation and the determination of mean nanoparticle size (hydrodynamic diameter) using batch-mode dynamic light scattering (DLS) in dilute aqueous suspensions. We then demonstrate this method for 30 nm colloidal gold. |
| Citation: |
Characterization of Nanoparticles Intended for Clinical Applications |
| Publisher: |
Humana Press, Totowa, NJ |
| Pages: |
pp. 35 - 52 |
| Keywords: |
Hydrodynamic size; dynamic light scattering; photon correlation spectroscopy; quasi-elastic light scattering; DLS; PCS; QELS; diffusion; diffusion coefficient; particle size |
| Research Areas: |
Nanomaterials |
