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Publication Citation: Measuring the Hydrodynamic Size of Nanoparticles in Aqueous Media Using Batch-Mode Dynamic Light Scattering

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Author(s): Vincent A. Hackley; Jeffrey D. Clogston;
Title: Measuring the Hydrodynamic Size of Nanoparticles in Aqueous Media Using Batch-Mode Dynamic Light Scattering
Published: January 01, 2011
Abstract: Particle size characterization is of particular importance to nanomedicine as ,nanoŠ is a dimensional definition, and the size similarity of nanoparticles to biological moieties is believed to impart many of their unique medical properties. Here we present a method for sample preparation and the determination of mean nanoparticle size (hydrodynamic diameter) using batch-mode dynamic light scattering (DLS) in dilute aqueous suspensions. We then demonstrate this method for 30 nm colloidal gold.
Citation: Characterization of Nanoparticles Intended for Clinical Applications
Publisher: Humana Press, Totowa, NJ
Pages: pp. 35 - 52
Keywords: Hydrodynamic size; dynamic light scattering; photon correlation spectroscopy; quasi-elastic light scattering; DLS; PCS; QELS; diffusion; diffusion coefficient; particle size
Research Areas: Nanomaterials