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Publication Citation: Characterization of Laminin on Silanized Polydimethylsiloxane

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Author(s): Joy P. Dunkers; Lisa M. Hughes; Hae-Jeong Lee; Marvi Matos; Marcus T. Cicerone;
Title: Characterization of Laminin on Silanized Polydimethylsiloxane
Published: August 21, 2008
Abstract: In this work, we characterize a protein surface on a flexible polydimethylsiloxane substrate (PDMS) capable of undergoing strain. We compare the results from two different surface treatments: physically adsorbed laminin on PDMS and laminin deposited on silane treated PDMS. Immunofluorescence and x-ray reflectivity were used to measure the amount of laminin from each surface treatment. Vascular smooth muscle cell attachment and proliferation were compared between the methods. Additional work will concentrate on evaluating the robustness of surface treatments under strain.
Conference: ACS Fall Meeting
Pages: 2 pp.
Location: Philadelphia, PA
Dates: August 17-21, 2008
Keywords: laminin, polydimethylsiloxane, smmoth muscle cells, X-ray reflectivity
Research Areas: Biomaterials
PDF version: PDF Document Click here to retrieve PDF version of paper (1MB)