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Publication Citation: A New Synthetic Method for Controlled Polymerization of HPMA Using a Microfluidic System

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Author(s): Tao Wu; Ying Mei; J Cabral; Chang Xu; Kathryn L. Beers;
Title: A New Synthetic Method for Controlled Polymerization of HPMA Using a Microfluidic System
Published: February 01, 2004
Abstract: Atom transfer radical polymerizations (ATRP) were performed in a microfluidic channel, fabricated in a solvent resistant polymer matrix. Compared to conventional batch polymerization, microfluidic platforms offer a unique opportunity to handle small samples in high volumes with both time and space control. In our experiments, we show continuous polymerization of hydroxyl propyl methacrylate (HPMA) in the microfluidic channel. We are able to control molecular weight by regulating reaction times using different constant pumping rate. Alternately, we can control input of reagent ratios to control molecular weight, composition and architecture of the polymer output. This method is one piece of a larger platform being designed to formulate polymeric materials using microfluidic technology.
Conference: Sigma Xi Web Page
Proceedings: Sigma Xi Postdoctoral Poster Presentations, 2004
Volume: 126(32)
Dates: February 19-20, 2004
Keywords: controlled polymerization;HPMA;microfluidic system;synthetic method
Research Areas: Microfluidics, Polymers
PDF version: PDF Document Click here to retrieve PDF version of paper (79KB)