| Author(s): |
Marcus T. Cicerone; Joy P. Dunkers; N Washburn; |
| Title: |
Towards In-Situ Monitoring of Cell Growth in Tissue Engineering Scaffolds: High Resolution Optical Techniques |
| Published: |
January 12, 2004 |
| Abstract: |
Inability to obtain cellular-level information about progress of cell growth in tissue-engineering (TE) scaffolds is a pervasive problem. We demonstrate that a confocal microscope with two collinear contrast mechanisms, optical coherence, and fluorescence, can be used to perform non-destructive imaging of a polymer TE scaffold containing osteoblasts. We show that the combination of the techniques shows promise for in situ measurements of cell growth in a bioreactor, even for highly opaque TE scaffolds. |
| Citation: |
Tissue Engineering |
| Pages: |
8 pp. |
| Keywords: |
coherence;florescence;microscopy;morphology;OCT;scaffold;tissue engineering |
| Research Areas: |
Biomaterials, Tissue Engineering |
| PDF version: |
 Click here to retrieve PDF version of paper (314KB) |
