Ethyl-Α-Hydroxymethylacrylate, a Novel Isomeric Analog of 2-Hydroxyethyl Methacrylate (HEMA)

Published

January 1, 2000

Author(s)

Joseph M. Antonucci, J W. Stansbury, Bruce O. Fowler

Abstract

Hema (2-hydroxyethyl methacrylate), a hydrophilic surface active monomer, is widely used in dental adhesive systems and in its polymeric forms in numerous biomedical applications. Poly(HEMA) was the first synthetic hydrogel intended for use as a biomaterial. Some of the traditional uses of HEMA polymers and copolymers include soft contact lenses, intraocular lenses, vascular grafts, soft tissue substitutes and as hydrogels for controlled release delivery systems. HEMA also has found use in the formulation of photocurable bioactive composites with remineralization potential. Recently a unique isomeric analog of HEMA, ethyl-1-hydroxymethylacrylate (EHMA), was synthesized. This study describes a high yield synthetic method for the preparation of EHMA and compares the bulk polymerizability of EHMA and HEMA.

Proceedings Title

The 6th World Biometerials Congress

Volume

41(2)

Conference Dates

May 15-20, 2000

Conference Location

Kameula, HI

Conference Title

World Biomaterials Congress

Pub Type

Conferences

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Keywords

2-hydroxyethyl methacrylate, degree of conversion, ethyl-α-hydroxyethyl methacrylate, hydrophilicity, isomers, polymerizable

Citation

Antonucci, J. , Stansbury, J. and Fowler, B. (2000), Ethyl-Α-Hydroxymethylacrylate, a Novel Isomeric Analog of 2-Hydroxyethyl Methacrylate (HEMA), The 6th World Biometerials Congress, Kameula, HI, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=851627 (Accessed April 23, 2024)