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Publication Citation: Ethyl-Α-Hydroxymethylacrylate, a Novel Isomeric Analog of 2-Hydroxyethyl Methacrylate (HEMA)

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Author(s): Joseph M. Antonucci; J W. Stansbury; Bruce O. Fowler;
Title: Ethyl-Α-Hydroxymethylacrylate, a Novel Isomeric Analog of 2-Hydroxyethyl Methacrylate (HEMA)
Published: January 01, 2000
Abstract: Hema (2-hydroxyethyl methacrylate), a hydrophilic surface active monomer, is widely used in dental adhesive systems and in its polymeric forms in numerous biomedical applications. Poly(HEMA) was the first synthetic hydrogel intended for use as a biomaterial. Some of the traditional uses of HEMA polymers and copolymers include soft contact lenses, intraocular lenses, vascular grafts, soft tissue substitutes and as hydrogels for controlled release delivery systems. HEMA also has found use in the formulation of photocurable bioactive composites with remineralization potential. Recently a unique isomeric analog of HEMA, ethyl-1-hydroxymethylacrylate (EHMA), was synthesized. This study describes a high yield synthetic method for the preparation of EHMA and compares the bulk polymerizability of EHMA and HEMA.
Conference: World Biomaterials Congress
Proceedings: The 6th World Biometerials Congress
Volume: 41(2)
Location: Kameula, HI
Dates: May 15-20, 2000
Keywords: 2-hydroxyethyl methacrylate;degree of conversion;ethyl-α-hydroxyethyl methacrylate;hydrophilicity;isomers;polymerizable
Research Areas: Dental, Polymers
PDF version: PDF Document Click here to retrieve PDF version of paper (484KB)