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Publication Citation: Determination of Lipid Phase Transition Temperatures in Hybrid Bilayer Membranes

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Author(s): Neil A. Anderson; Lee J. Richter; John C. Stephenson; Kimberly A. Briggman;
Title: Determination of Lipid Phase Transition Temperatures in Hybrid Bilayer Membranes
Published: September 09, 2006
Abstract: The main gel to liquid crystal (LC) phase transition temperature, Tm, of the lipid monolayers in hybrid bilayer membranes (HBMs) was investigated using vibrational sum frequency spectroscopy (VSFS). The unique sensitivity of VSFS to probe order/disorder transitions was used to determine Tm for a series of saturated phosphatidylcholines on octadecanethiolate self assembled monolayers (SAMs). The values obtained for Tm average 10 degrees C higher for the lipids in HBMs than for the corresponding lipids in vesicles in solution.
Citation: Journal of the American Chemical Society
Volume: 22
Issue: 20
Pages: pp. 8333 - 8336
Keywords: hybrid bilayer membranes;phase transition temperature.;SFG;supported bilayer membrane mimics;vibrational sum frequency spectroscopy
Research Areas: Biological Physics, Physical Measurements, Nonlinear Optical Spectroscopy, Bioscience & Health
PDF version: PDF Document Click here to retrieve PDF version of paper (75KB)