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The effect of hydrocarbon fuel type on the ranking of inhibitor effectiveness has been investigated through computer simulations. The approach involves carrying out sensitivity analysis on the detailed kinetics of the combustion of C1-C4 hydrocarbons. It is demonstrated that the main reactions determining burning velocities are the same. Similar suppressant rankings from the combustion of different hydrocarbon fuels are largely due to the reactions of a number of small radicals that are common to all of these systems. Inhibitor addition reduces the concentration of these radicals with the active agents being recycled by the common breakdown products of the fuel.Inhibitor effectiveness of various additives in a variety of fuels was analyzed using experimental data on the effects of additives on burning velocity in small additive concentration ranges. An