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Contactless Differential Conductivity Detection

Published

Author(s)

Gordon A. Shaw, David J. Ross, Steven E. Fick, Wyatt N. Vreeland

Abstract

We propose a new technique, contactless differential conductivity detection (CDCD,) to improve the detection limit of contactless conductivity detection for capillary and microchannel electrophoresis. By exploiting a 3-electrode differential configuration, CDCD greatly reduces the dominant noise source in contactless conductivity detection: temperature fluctuations within the measurement system. This will be a particularly important feature for high-conductivity samples, which are most susceptible to thermal noise. The reduced sensitivity of CDCD to temperature fluctuations and its potential suitability for low-power operation will also make this an excellent candidate for field-portable and point-of-application uses where optical detection strategies may be more difficult to implement.
Proceedings Title
Proceedings of microTAS 2008
Conference Dates
October 12-16, 2008
Conference Location
San Diego, CA
Conference Title
microTAS 2008

Keywords

contactless conductivity detection, detector, electrophoresis

Citation

Shaw, G. , Ross, D. , Fick, S. and Vreeland, W. (2008), Contactless Differential Conductivity Detection, Proceedings of microTAS 2008, San Diego, CA, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=824689 (Accessed April 18, 2024)
Created October 12, 2008, Updated February 19, 2017