Biological physics

News and Updates

NIST Researchers Develop a Breakthrough COVID-19 Detection Technology

October 2, 2023

“Only connect” is the most famous line in the British novelist E. M. Forster’s writings. Forster was urging the readers of his book Howard’s End to make

white matter mimic in the bottom half of the artificial cranium

Lessons from an Experimental Brain Phantom

July 12, 2023

Researchers at the National Institute of Standards and Technology (NIST) and colleagues have developed a novel, anatomically accurate reference model of the

New NIST Licensing Opportunity Teems with Potential Applications

July 5, 2023

Max Planck, one of the Twentieth Century’s most eminent physicists, observed, "An experiment is a question that science poses to Nature, and a measurement is

Projects and Programs

viral vector illustration with RNA seen within the capsid

Gene Delivery Particle Analysis with High-Throughput Light Scattering Microscopy

Ongoing

Calibration Services: National Air-Kerma Standard for Electronic Brachytherapy

Ongoing

The Dosimetry Group calibrates well-type ionization chambers using Xoft miniature x-ray sources, which provide low-energy x-rays (< 50 keV) for electronic

Nano-biophotonics for molecular imaging

Ongoing

Biophotonics is at the intersection of photonics and biology where light is used to image, detect, and manipulate biological materials. This project addresses

Protocol for Preparing Fibrillar Collagen Matrices on Untreated Polystyrene Labware (Petri)*: A Potential Reference Extracellular Matrix With Robust and Reproducible Cell Responses

Ongoing

Background: Collagen type 1 is the most prevalent extracellular protein in connective tissue, and is part of the family of collagens that are fibril forming

Publications

Quantifying a light-induced energetic change in bacteriorhodopsin by force spectroscopy

February 7, 2024

Author(s)

David Jacobson, Thomas T. Perkins

Influence of fluorescence lifetime selections and conformational flexibiiliy on brightness of FusionRed variants

February 5, 2024

Author(s)

Srijit Mukherjee, Nancy Douglas, Ralph Jimenez

Narrowing Signal Distribution by Adamantane Derivatization for Amino Acid Identification Using α-Hemolysin Nanopore

January 24, 2024

Author(s)

Xiaojun Wei, Dumei Ma, Junlin Ou, Ge Song, Jiawei Guo, Joseph Robertson, Yi Wang, Qian Wang, Chang Liu

Nanopores have demonstrated remarkable sensitivity as biosensors, enabling the sequencing of DNA and RNA at the single-molecule level. The rapid progress in

High-resolution infrared spectroscopy of jet cooled cyclobutyl in the α-CH stretch region: Large-amplitude puckering dynamics in a 4-membered ring radical

January 5, 2024

Author(s)

Ya-Chu Chan, David Nesbitt

Software

NIST's Integrated Colony Enumerator (NICE)

January 4, 2021

Enumeration of bacterial colonies on an agar plate is simple in concept, but automated colony counting is difficult due to variations in colony color, size

Tools and Instruments

Beamline 10: Quantitative Hyperspectral Infrared Microscopy

The new beamline 10, currently under construction, is intended for applications that make use of the super-thermal brightness from SURF in the near- to mid