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You searched on: Author: Walter Liggett Jr

Displaying records 1 to 10 of 26 records.
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1. Chapter - Batch effects and experimental noise in Microarray Analysis: sources and solutions. Microarray Gene Expressions: The Effects of Varying Certain Measurement Conditions.
Published: 11/2/2009
Author: Walter S Liggett Jr
Abstract: This chapter explores measurements from an experiment with a batch effect induced by switching the mass of RNA analyzed from 400 ng to 200 ng. The experiment has as additional factors the RNA material (liver, kidney, and two mixtures) and the RNA so ...

2. Technical Variation in Modeling the Joint Expression of Several Genes
Published: 10/25/2007
Author: Walter S Liggett Jr
Abstract: Biological studies based on expression microarrays often depend crucially on comparison of expression measurements that are subject to technical variation associated with changes in time, laboratory or other measurement conditions. If a biological st ...

3. Predictability of the Technical Variation in Gene Expression Measurements
Published: 10/1/2006
Author: Walter S Liggett Jr
Abstract: Technical variation in whole-genome, single-probe, one-color microarrays has some common properties that are the subject of this paper. One such property, which is evidenced in measurement of different materials in the same laboratory, involves non-l ...

4. System Performance and Natural Language Expression of Information Needs
Published: 1/5/2005
Authors: Walter S Liggett Jr, C E Buckley
Abstract: Consider information retrieval systems that respond to a query (a natural language statement of a topic, an information need) with an ordered list of 1000 documents from the document collection. From the responses to queries that all express the sam ...

5. Nonparametric and Semiparametric Models in Comparison of Observations of a Particle-Size Distribution
Published: 6/1/2003
Author: Walter S Liggett Jr
Abstract: Testing hypotheses about pairs of unnormalized histograms motivates this paper. The histograms contain particle counts for particle-size intervals. The analysis involves generalized-linear-model fitting of cubic splines with irregularly-spaced kno ...

6. An Empirical Approach to Determining Rockwell Hardness Measurement Uncertainty
Published: 7/1/2002
Authors: Samuel Rea Low III, Walter S Liggett Jr
Abstract: Characteristics of the empirically developed Rockwell hardness test make it difficult to determine measurement uncertainty using methods traditionally applied to other metrological measurements. An empirical approach to determining Rockwell hardness ...

7. Query Expansion Seen Through Return Order of Relevant Documents
Published: 10/10/2001
Author: Walter S Liggett Jr
Abstract: There is a reservoir of knowledge in data from the TREC evaluations that analysis of precision and recall leaves untapped. This knowledge leads to better understanding of query expansion as this paper demonstrates. In many TREC tasks, the system re ...

8. Understanding TREC Results - the Role of Statistics
Published: 8/1/2001
Authors: Walter S Liggett Jr, Paul Douglas Over
Abstract: The challenge in empirical development of information retrieval systems at TREC is obtaining general conclusions from IR system responses to a sample of perhaps 50 topics, that is, 50 statements of information need. Treating such a sample as a simpl ...

9. The Effect of Query Choice on Information Retrieval
Published: 7/20/2001
Authors: Walter S Liggett Jr, C E Buckley
Abstract: Analysis of the Query Track of the Eighth Text Retrieval Conference (TREC-8) shows how the presence or absence of a word or two in a query can make a large difference in information retrieval performance. The Query Track contains results from 8 syst ...

10. Capability in Rockwell C Scale Hardness
Series: Journal of Research (NIST JRES)
Published: 7/1/2000
Authors: Walter S Liggett Jr, Samuel Rea Low III, David J Pitchure, Jun-Feng Song
Abstract: To determine the capability of a system for Rockwell C scale hardness, one must make test measurements, which can be planned and interpreted as explained in this paper. Uncertainty, which is one part of capability, is treated specifically, and produ ...

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