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Author: peter vallone
Displaying records 11 to 20 of 39 records.
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11. The evaluation of an autosomal SNP 12-plex assay
Peter M Vallone, Amy E. Decker, Michael D Coble, John M Butler
SNPs have the potential to play a useful role in human identification testing. Small PCR amplicon sizes associated with SNP typing technologies make SNPs attractive for typing degraded DNA or other low copy number situations. SNP markers can be usefu ...
12. Analysis of DNA Single Nucleotide Polymorphisms by Mass Spectrometry
Peter M Vallone, John M Butler
Single nucleotide polymorphisms(SNP) are the most frequent form of DNA sequence variation in the human genome and are becoming increasingly useful as genetic markers for genome mapping studies, medical diagnostics, and human identity testing. The pri ...
13. Allele frequencies for 27 Y-STR loci with U.S. Caucasian, African American, and Hispanic samples
John M Butler, Amy E. Decker, Peter M Vallone, Margaret C Kline
14. Effective Strategies for Forensic Analysis in the Mitochondrial DNA Coding Region
Michael D Coble, Peter M Vallone, Rebecca S Just, Toni M Diegoli, Brion C Smith, T. J. Parsons
Recently, it has been recognized that accessing information in the mitochondrial DNA (mtDNA) coding region can provide additional forensic discrimination with respect to the standard typing of the D-loop region, augmenting the sometimes rather limite ...
15. Testing Candidate DNA Quantitation Standards with Several Real-Time Quantitative PCR Methods
Margaret C Kline, Peter M Vallone, Amy E. Decker, Janette W. Redman, David Lee Duewer, John M Butler
16. Chromosomal Duplications Along the Y-Chromosome and Their Potential Impact on Y-STR Interpretation
John M Butler, Amy E. Decker, Margaret C Kline, Peter M Vallone
Y-chromosome short tandem repeat (Y-STR) markers are being touted as potential tools for distinguishing low levels of male DNA in the presence of excess female DNA as is present in many sexual assault samples. Usually single copy Y-STR loci produce a ...
17. Genotyping SNPs Using a UV Photocleavable Oligonucleotide in MALDI-TOF MS
Peter M Vallone, K Fahr, M Kostrzewa
Matrix assisted laser desorption time-of-flight mass spectrometry (MALDI-TOF MS) coupled with allele specific primer extension is a proven method for typing single nucleotide polymorphisms (SNPs). A novel modification upon this methodology is the in ...
18. Mitochondrial DNA Typing Screens With Control Region and Coding Region SNPs
Margaret C Kline, Peter M Vallone, Janette W. Redman, David Lee Duewer, C D Calloway, John M Butler
Mitochondrial DNA (mtDNA) analysis has found an important niche in forensic DNA typing. It is used with highly degraded samples or low-copy number materials such as might be found from shed hair or bones exposed to severe environmental conditions. ...
19. An Allele-Specific Primer Extension Assay for the Detection of 11 SNPs Located in the Mitochondrial Genome
Peter M Vallone, Michael Coble, R S Just, John M Butler, Thomas J Parsons
The typing of single nucleotide polymorphisms (SNPs) located throughout the mitochondrial genome (mtGenome) allows for differentiation between individulas possessing an identical HVa/HV2 sequence. A set of 11 SNPs selected for separating the most co ...
20. Multiplexed assays for evalution of Y-SNP markers in U.S populations. Progress in Forensic Genetics 10, Elsevier Science.
Peter M Vallone