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You searched on: Author: john kasianowicz Sorted by: title

Displaying records 1 to 10 of 64 records.
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1. Analytical Approaches for Studying Transporters, Channels, and Porins
Published: 12/15/2012
Authors: Joseph William Robertson, John J Kasianowicz, Soojay (Soojay) Banerjee

2. Anthrax Toxin Functional Assay: Lethal Factor Binding to Protective Antigen Ion Channel
Published: Date unknown
Authors: Kelly Halverson, R G Panchal, T L Nguyen, S Little, Martin Misakian, Sina Bavari, John J Kasianowicz
Abstract: Bacillus anthracis secretes three toxins (protective antigen, PA; lethal factor, LF; and edema factor, EF) that are the molecular basis of anthrax-induced cell death. We studied the functional interaction between LF and activated PA (PA63) in planar ...

3. Changes in Ion Channel Geometry Resolved to Sub-angstrom Levels via Single Molecule Mass Spectrometry
Published: 10/29/2010
Authors: Joseph William Robertson, John J Kasianowicz, Joseph E. Reiner

4. Charged Polymer Membrane Translocation
Published: 8/22/2002
Authors: T Ambjornsson, S. P. Apell, Z Konkoli, E A Di Marzio, John J Kasianowicz

5. Conductance and Ion Selectivity of a Mesoscopic Protein Nanopore Probed with Cysteine Scanning Mutagenesis
Published: 11/1/2005
Authors: P Merzlyak, Maria-Fatima P. Capistrano, Angela Valeva, John J Kasianowicz, Oleg V Krasilnikov

6. Conductance and ion selectivity of a mesoscopic protein nanopore probed with cysteine scanning mutagenesis
Published: 11/1/2005
Authors: Petr Merzlyak, Maria-Fatima P. Capistrano, Angela Valeva, John J Kasianowicz, Oleg V Krasilnikov
Abstract: Nanometer-scale, proteinaceous pores are the basis of ion and macromolecular transport in cells and organelles. Recent studies suggest that ion channels and synthetic nanopores may prove useful in biotechnological applications. To better understand t ...

7. Diffusion Bias and Photophysical Dynamics of Single Molecules in Unsupported Lipid Bilayer Membranes Probed with Confocal Microscopy
Published: 7/1/2000
Authors: D L. Burden, John J Kasianowicz
Abstract: We utilize scanning confocal fluorescence microscopy to interrogate single fluorescent lipid molecules in unsupported planar bilayers. At high photon flux, an optical trapping effect appears that is approximately 100,000 times larger than predicted ...

8. Disease Detection and Management via Single Nanopore-Based Sensors
Published: 12/15/2012
Authors: Joseph E Reiner, Arvind Kumar Balijepalli, Joseph William Robertson, Jason P Campbell, John S Suehle, John J Kasianowicz

9. Driven DNA Transport Into an Asymmetric Nanometer-Scale Pore
Published: 10/2/2000
Authors: S. E. Henrickson, Martin Misakian, B Robertson, John J Kasianowicz
Abstract: To understand the mechanism by which individual DNA molecules partition into a nanometer-scale pore, we studied the concentration and voltage dependence of polynucleotide-induced current blockades of single a-hemolysin ionic channels. At fixed singl ...

10. Dynamic Partitioning of Neutral Polymers into a Single Ion Channel
Published: 6/1/1999
Authors: S. M. Bezrukov, John J Kasianowicz
Abstract: Polymers partitioning into highly confined spaces can be studied using single nanometer-scale pores formed by protein ion channels. The ionic conductance of a channel depends on the state of occupancy of the pore by polymer and serves as a measure o ...

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