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Author: pawel jaruga

Displaying records 51 to 57.
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51. Mechanisms and Measurement of Oxidative Damage to DNA
Published: 3/1/2001
Authors: M. Dizdaroglu, Pawel Jaruga, H Rodriguez
Abstract: Free radicals are produced in cells by normal metabolism and by exogenous sources. These species cause oxidative damage to DNA and generate multiple products including modified bases and sugars, strands breaks and DNA-protein crosslinks by a variety ...

52. Measurement of 8-Hydroxy-2'-Deoxyguanosine in DNA by High-Performance Liquid Chromatography-Mass Spectrometry: Comparison with Measurement by Gas Chromatography-Mass Spectrometry
Published: 2/1/2001
Authors: M. Dizdaroglu, Pawel Jaruga, H Rodriguez
Abstract: Measurement of 8-hydroxy-2'-deoxyguanosine (8-OH-dGuo) in DNA by high-performance liquid chromatography/mass spectrometry (HPLC/MS) was studied. A methodology was developed for separation by LC of 8-OH-dGuo from intact and modified nucleosides i ...

53. Characterization and Mechanism of Action of Drosophila Ribosomal Protein S3 DNA Glycosylase Activity for the Removal of Oxidatively Damaged DNA Bases
Published: 12/26/1997
Authors: W. A. Deutsch, A. Yacoub, Pawel Jaruga, T. H. Zastawny, M Miral Dizdar

54. Kinetics of Excision of Purine Lesions from DNA by Escherichia coli Fpg Protein
Published: 2/1/1997
Authors: A Karakaya, Pawel Jaruga, V A Bohr, Arthur P Grollman, M Miral Dizdar

55. Oxidative DNA Base Damage and its Repair in Kidneys and Livers of Nickel(II)-treated Male F344 Rats
Published: 2/1/1997
Authors: K S Kasprzak, Pawel Jaruga, T H Zastawny, S L North, C W Riggs, R Olinski, M Miral Dizdar

56. Cellular DNA Biomarkers for the Safety of Tissue-Engineered Medical Products Using Artificial Skin as a Model
Published: Date unknown
Authors: H Rodriguez, C D O'Connell, Peter E. Dr. Barker, M. Dizdaroglu, Donald H Atha, Pawel Jaruga, M Birincioglu, M A Marino, P McAndrew
Abstract: Fundamental to the safety of many tissue-engineered medical products is how cells respond to a given polymer when implanted into the body. Assurance of cellular stability during the manufacturing, storage and shipment of such products is crucial to ...

57. Structural Alterations in the DNA of Stroma and Epithelium From the Female Breast
Published: Date unknown
Authors: Donald C Malins, Katie M Anderson, Pawel Jaruga, Callie R Ramsey, Naomi K Gilman, Virginia M Green, Steven W Rostad, Joanne T Emerman, M. Dizdaroglu
Abstract: Reciprocal interactions between the stroma and epithelium are considered to be intimately associated with the development of breast cancer. In studies of whole breast tissues, a keen interest exists in the occurrence of the mutagenic DNA lesions 8-h ...

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