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|Author(s):||Bret Windom; Thomas J. Bruno;|
|Title:||Novel Reduced Pressure-Balance Syringe for Chromatographic Analysis|
|Published:||November 19, 2010|
|Abstract:||When withdrawing a fluid sample from an apparatus at reduced pressures for additional chromatographic analyses, a gas tight plunger syringe proves ineffective as it does not create a substantial pressure differential to pull a fluid from a reduced pressure environment. Resulting from motivation to analyze distillate fractions from a reduced pressure advanced distillation curve (ADC) apparatus, a device was developed allowing one to withdraw precise amounts of sample from an apparatus operating at sub-ambient pressures. The new device uses an external vacuum source to evacuate a syringe barrel, extracting fluids from a chamber at pressures as low as 0.5 kPa. To demonstrate the operation of the newly developed device, ~10 υl of distillate fraction from the reduced pressure ADC apparatus were withdrawn and analyzed by gas chromatography mass spectrometry. Distillate extraction and analyses were performed on two fluids, a predefined validation mixture and commercial soy based biodiesel fuel. The new device is not limited to reduced pressure distillations and may be useful for a variety of applications in which further chemical/compositional analyses are desired on a fluid contained in a reduced pressure environment.|
|Citation:||Journal of Chromatography A|
|Pages:||pp. 7434 - 7439|
|Keywords:||chromatography, sampling, syringe, vacuum|
|Research Areas:||Chemical Analysis, Chemistry|