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Chemistry Programs & Projects

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Chemical Metrology for Metals, Ores, and Related Materials
Last Updated Date: 01/20/2015

A wide range of industrial sectors and their customers and suppliers are involved directly with NIST in the prioritization and development of … more

Establishing Measurement Traceability for Gaseous Mercury Emissions Monitoring
Last Updated Date: 01/20/2015

As a result of the environmental impact of mercury and the neurotoxic risk associated with trophic transfer of methyl mercury to humans, the … more

Chemical Metrology for Polymers Manufacturing
Last Updated Date: 01/20/2015

Chemical metrology for polymers manufacturing is a new area of endeavor for the Chemical Sciences Division. At the outset, efforts have involved … more

Renewal of NIST Benchmark SRMs for Accurate Determinations of Trace Elements in Serum and Liver Tissues
Last Updated Date: 01/20/2015

The Centers for Disease Control and Prevention (CDC) collects data on elemental composition of human body fluids and tissues as part of major … more

Advanced IC Interconnects - Process Metrology and Models
Last Updated Date: 01/20/2015

The objective for Advanced IC Interconnects is to provide measurement standards and advanced measurement methods supporting metrology needs of the … more

Gas and Particulate Concentration Measurements and Standards
Last Updated Date: 01/20/2015

The objective is to develop and demonstrate accurate and robust measurement approaches that will establish optical absorption line intensities … more

Fatty Acids in Human Serum and Plasma Quality Assurance Program
Last Updated Date: 01/20/2015

The National Institute of Standards and Technology (NIST) and the National Institutes of Health (NIH) Office of Dietary Supplements (ODS) have … more

Metrologies for Protein Structure, Function, and Modeling
Last Updated Date: 01/20/2015

NIST researchers in the Macromolecular Structure and Function Group are involved in a joint research program with scientists from the University … more

Electron Ionization Library Component of the NIST/EPA/NIH Mass Spectral Library and NIST GC Retention Index Database
Last Updated Date: 01/20/2015

The National Institute of Standards and Technology (NIST) has developed and maintains an Electron Ionization (EI) Library as part of the … more

Performance Metrics for Proteomics
Last Updated Date: 01/20/2015

In collaboration with the National Cancer Institute's Clinical Proteomic Technologies for Cancer (CPTC) , NIST researchers are developing specific … more

Peptide Mass Spectral Libraries
Last Updated Date: 01/20/2015

The National Institute of Standards and Technology is developing a peptide mass spectral library as an extension of the NIST/EPA/NIH Mass Spectral … more

Chromatographic Separation of Unfolded Proteins for Protein Quantification
Last Updated Date: 01/20/2015

NIST is developing methods for the quantification of protein biomarkers by mass spectrometry (MS). Stable isotope labeling of proteins/peptides … more

Development of Reference Methods and Reference Materials for the Determination of Cardiac Troponin I in Human Serum
Last Updated Date: 01/20/2015

Cardiac troponin I (cTnI) is considered the 'gold standard' for the diagnosis of myocardial infarction and the assessment of cardiac damage. Yet … more

Development of Proteomics-Based Methods for Protein Quantification
Last Updated Date: 01/20/2015

NIST is developing methods for the quantification of clinically-relevant protein biomarkers by mass spectrometry. Some methods are intended to … more

Development of a Reference Measurement Procedure for C-Reactive Protein in Human Serum
Last Updated Date: 01/20/2015

C-reactive protein (CRP) levels in serum or plasma have been used as an indicator of inflammation and infection. Recent evidence also suggests … more

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