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Search Publications by: Sheng Lin-Gibson (Fed)

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Displaying 51 - 75 of 115

Synthesis and Characterization of Elastin Mimetic Hybrid Polymers with Alternating Molecular Architecture and Elastomeric Properties

September 15, 2009
Author(s)
Sheng Lin-Gibson, Sarah E. Grieshaber, Alexandra J. Farran, Kristi L. Kiick, Xinqiao Jia
We are interested in developing elastin mimetic hybrid polymers (EMHPs) that capture the multiblock molecular architecture of tropoelastin as well as the remarkable elasticity of mature elastin. In this study, multiblock EMHPs containing flexible synthetic

Microbial colonization on polymers: Effects of sample preparation and incorporation of quaternary ammonium salts

September 13, 2009
Author(s)
Nancy J. Lin, Diana N. Zeiger, Joseph M. Antonucci, Bruce O. Fowler, Christopher M. Stafford, Sheng Lin-Gibson
Controlling bacterial growth in the oral environment presents many challenges. To address these challenges, new materials and treatments are needed along with controlled, reproducible methods to evaluate their efficacy. In this study, a reproducible method

Effects of filler type and content on mechanical properties of photopolymerizable composites determined using a two-dimensional gradient platform

February 5, 2009
Author(s)
Sheng Lin-Gibson, Li Piin Sung, Haiqing Hu, Aaron M. Forster, Nancy J. Lin
Photopolymerizable dental composites have complex processing conditions and multi-component formulations that affect the final properties. Combinatorial screening is a useful approach for evaluating multiple properties of the composites. A single test

Beta-Sheet Formation and RGD-Presentation Effects on Osteoblast Differentiation

November 15, 2008
Author(s)
Carl G. Simon Jr., Matthew Becker, Sheng Lin-Gibson, Kristen E. Roskov, David L. Kaplan, Abby W. Morgan
This report highlights our recent investigation into -sheet formation and RGD epitope presentation on the surface of blended silk films.1 Surface characterization of biomaterials for tissue engineering applications is of great importance to understand how

Monitoring Alignment of Osteoblast Cells Directed by Gradient Nanopatterns

April 6, 2008
Author(s)
Jirun Sun, Yifu Ding, Nancy J. Lin, Hyun Wook Ro, Christopher L. Soles, Sheng Lin-Gibson
We investigated the behavior of pre-osteoblasts cultured on polystyrene and photopolymerized ethoxylated bisphenol-A dimethacrylate gradient patterns. Gradient patterns varying in height from several hundred to 0 nm were prepared using nanoimprinting

X-Ray Imaging Optimization of 3D Tissue Engineering Scaffolds via Combinatorial Fabrication Methods

April 1, 2008
Author(s)
Yanyin Yang, Shauna M. Dorsey, Matthew Becker, Sheng Lin-Gibson, Gary E. Schumacher, Glenn M. Flaim, J Kohn, Carl G. Simon Jr.
We have developed a combinatorial method for determining optimum tissue scaffold composition for imaging by X-ray techniques. X-ray radiography and microcomputed tomography enable non-invasive imaging of implanted materials in vivo and in vitro

Non-Brownian Microrheology of a Fluid Gel Interface

February 20, 2008
Author(s)
Erik K. Hobbie, Sheng Lin-Gibson, S K. Kumar
We use stroboscopic video microscopy to study the motion of a sheared fluid-gel interface. External mechanical noise plays a role analogous to temperature, but with a low-frequency breakdown of linear response consistent with an underlying instability. We

Mapping Cell Distribution in Amorphous Scaffolds using Confocal Microscopy

August 19, 2007
Author(s)
Jirun Sun, Nancy Lin, Marcus T. Cicerone, Sheng Lin-Gibson
One common method for probing cell-material interactions is direct visualization via confocal laser scanning microscopy, a technique widely used for studying biological systems. However, confocal microscopy has limited depth penetration for imaging cells

Relationship between dispersion metric and properties of PMMA/SWNT nanocomposites

June 13, 2007
Author(s)
Takashi Kashiwagi, Jeffrey Fagan, Jack F. Douglas, Kazuya Yamamoto, N. Alan Heckert, Stefan D. Leigh, Jan Obrzut, Fangming Du, Minfang Mu, Sheng Lin-Gibson, K Winey, R Haggenmueller
Particle spatial dispersion is a crucial characteristic of polymer composite materials and this property is recognized as especially important innanocomposite materials due to the general tendency of nanoparticles to aggregate under processing conditions

Rapid Assessment of Dental Polymers Using Gradient Samples

April 18, 2007
Author(s)
Nancy J. Lin, Peter Drzal, Sheng Lin-Gibson
Dental composites are widely used yet still face challenges including incomplete conversion, polymerization shrinkage, and poor adhesion to tooth structures. High-throughput techniques to quickly assess several material properties in a combinatorial manner