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Search Publications by: Alessandro Tona (Fed)

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Displaying 26 - 34 of 34

Mechanical Stability of Collagen Fibril Networks

November 1, 2005
Author(s)
Gordon A. Shaw, Dennis P. McDaniel, John T. Elliott, Alessandro Tona, Anne L. Plant
Thin films of type 1 collagen fibril networks fabricated on alkanethiol-functionalized surfaces have been previously shown to provide an excellent protein matrix for cultured cells in applications such as drug toxicity studies and studies of cell signaling

Osteoblast Cell Membrane Hybrid Bilayers for Studying Cell-Cell Interactions

September 30, 2003
Author(s)
John T. Elliott, Alessandro Tona, John T. Woodward IV, Curtis W. Meuse, H M. Elgendy, Anne L. Plant
Osteopath-like cells were grown on a surface that presents cell membrane components to the cells in culture. The culture surface was a bilayer formed by the interaction of osteoblast plasma membrane vesicles with an alkanethiol monolayer. We examined the

Combinatorial Characterization of Cell Interactions with Polymer Surfaces

September 1, 2003
Author(s)
J C. Meredith, J L. Sormana, B G. Keselowsky, A J. Garcia, Alessandro Tona, Alamgir Karim, Eric J. Amis
The combinatorial library and high-throughput techniques presented here allow rapid, efficient, and accurate exploration of the effects of microstructure and surface features on cell adhesion and proliferation. The new technique serves as a natural

Thin Films of Collagen Affect Smooth Muscle Cell Morphology

March 4, 2003
Author(s)
John T. Elliott, Alessandro Tona, John T. Woodward IV, P L. Jones, Anne L. Plant
The purpose of this study was to provide a reproducible method for applying collagen to surfaces on which cells can be grown, and to characterize the resulting thin films of collagen protein with respect to molecular structure and cellular response

Co-Extrusion of Biocompatible Polymers for Scaffolds With Co-Continuous Morphology

April 1, 2002
Author(s)
N. R. Washburn, Carl Simon Jr., Alessandro Tona, H M. Elgendy, Alamgir Karim, Eric J. Amis
A methodology for the preparation of porous scaffolds for tissue engineering using co-extrusion is presented. Poly(espilon-caprolactone) is blended with poly(ethylene oxide) in a twin-screw extruder to form a two-phase material with micron-sized domains