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Search Publications by: John T. Elliott (Fed)

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Displaying 51 - 74 of 74

Cell volume distributions reveal cell growth rates and division times

March 7, 2009
Author(s)
Michael W. Halter, John T. Elliott, Joseph B. Hubbard, Alessandro Tona, Anne L. Plant
A population of cells in culture displays a range of phenotypic responses, even when those cells are derived from a single cell and are exposed to a homogeneous environment. Phenotypic variability can have a number of sources, including the variable rates

The Stiffness of Collagen Fibrils Influences Vascular Smooth Muscle Cell Phenotype

March 1, 2007
Author(s)
Dennis P. McDaniel, Gordon A. Shaw, John T. Elliott, Kiran Bhadriraju, Curtis W. Meuse, Koo-Hyun Chung, Anne L. Plant
Cells receive signals from the extracellular matrix through receptor-dependent interactions, but they are also influenced by the mechanical properties of the matrix. While bulk properties of substrates have been shown to effect cell behavior, we show here

Mechanical Stability of Collagen Fibril Networks

November 1, 2005
Author(s)
Gordon A. Shaw, Dennis P. McDaniel, John T. Elliott, Alessandro Tona, Anne L. Plant
Thin films of type 1 collagen fibril networks fabricated on alkanethiol-functionalized surfaces have been previously shown to provide an excellent protein matrix for cultured cells in applications such as drug toxicity studies and studies of cell signaling

Manipulating Cell Adhesion on Gradient Poly(2-Hydroxyethyl Methacrylate)-Grafted Surfaces

April 1, 2005
Author(s)
Ying Mei, Tao Wu, Chang Xu, K J. Langenbach, John T. Elliott, B D. Vogt, Kathryn L. Beers, Eric J. Amis, N Washburn
In this study, a simple and versatile method was developed to prepare the low grafting density initaitor gradient, which was combined with surface initiated atom transfer radical polymerizations (ATRP) to produce a well defined poly(2-hydroxyethyl

Osteoblast Cell Membrane Hybrid Bilayers for Studying Cell-Cell Interactions

September 30, 2003
Author(s)
John T. Elliott, Alessandro Tona, John T. Woodward IV, Curtis W. Meuse, H M. Elgendy, Anne L. Plant
Osteopath-like cells were grown on a surface that presents cell membrane components to the cells in culture. The culture surface was a bilayer formed by the interaction of osteoblast plasma membrane vesicles with an alkanethiol monolayer. We examined the

Biomimetic Membranes on Metal Supports

May 1, 2003
Author(s)
John T. Elliott, Curtis W. Meuse, Vitalii I. Silin, Susan T. Krueger, John T. Woodward IV, T Petralli-Mallow, Anne L. Plant
Biological membranes are complex and dynamic structures. The biological functions associated with membranes involve a number of different molecular species, and theories of how the molecular species are organized are still evolving. The fluid mosaic model

Thin Films of Collagen Affect Smooth Muscle Cell Morphology

March 4, 2003
Author(s)
John T. Elliott, Alessandro Tona, John T. Woodward IV, P L. Jones, Anne L. Plant
The purpose of this study was to provide a reproducible method for applying collagen to surfaces on which cells can be grown, and to characterize the resulting thin films of collagen protein with respect to molecular structure and cellular response

Indicator Cells Assist the Development of Tissue Engineering Products

January 1, 2003
Author(s)
Anne L. Plant, John T. Elliott, K J. Langenbach
The field of tissue engineering holds great promise. The premise is that living cells can be coaxed to differentiate, organize, and regenerate normal physiological function in diseased and damaged tissues. This outcome will not be achieved, however