To support the development of synthetic biology as an engineering discipline, we are working with partners at other institutions and agencies to develop quantitative methods to characterize engineered microbial strains and genetic circuit elements, such as promotors, terminators, enhancers, and ribosome binding sites.
We are working to develop standardized measurement assays and reporting characteristics for genetic circuit elements and establish reference strains and materials to support predictive design, by ensuring comparability of data between different research laboratories.
Science, 25 Mar 2016, Vol. 351, 6280
Clyde A. Hutchison III, Ray-Yuan Chuang, Vladimir N. Noskov, Nacyra Assad-Garcia, Thomas J. Deerinck, Mark H. Ellisman, John Gill, Krishna Kannan, Bogumil J. Karas, Li Ma1, James F. Pelletier, Zhi-Qing Qi, R. Alexander Richter, Elizabeth A. Strychalski, Lijie Sun, Yo Suzuki, Billyana Tsvetanova, Kim S. Wise, Hamilton O. Smith, John I. Glass, Chuck Merryman, Daniel G. Gibson, J. Craig Venter.