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Mickelene Hoggard

Display Name

Hoggard, Mickelene

First Name

Mickelene

Middle Name/Initial

F

Last Name

Hoggard

Phone Number

(843) 762-8950

Email Address

CPR ID

213897

Staff Type

NIST Employee

Campus

Mailing Address

United States

Mail Stop

8390

Organizational Unit

Division Name

Chemical Sciences Division

Division Code

646

Group Name

Marine Biochemical Sciences Group

Group Code

09

Access Rights

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Meghan Grandal

Display Name

Grandal, Meghan

First Name

Meghan

Middle Name/Initial

K

Last Name

Grandal

Phone Number

(843) 762-8924

Email Address

CPR ID

213480

Staff Type

NIST Employee

Campus

Mailing Address

United States

Mail Stop

8390

Organizational Unit

Division Name

Chemical Sciences Division

Division Code

646

Group Name

Marine Biochemical Sciences Group

Group Code

09

Access Rights

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Ben Neely

Display Name

Neely, Ben

Staff Photo

First Name

Benjamin

Alternate First Name

Ben

Middle Name/Initial

A

Last Name

Neely

Alternate Last Name

Neely

Phone Number

(843) 762-8999

Email Address

CPR ID

212590

Staff Type

NIST Employee

Staff Bio

Ben Neely's post-graduate career has focused on developing novel methods to interface classical proteomics and next generation mass spectrometers in order to facilitate analysis of high-dimensional proteomic data. Broadly, his research has focused on the use of mass spectrometry to identify, quantify, and qualify candidate biomarkers in biological samples (fluids or tissue) that can be used to diagnose and/or predict disease. Specifically, this includes identifying patterns of transcript/protein/lipid/glycan changes that can be used to discriminate between populations/disease, or that give insight to an underlying disease state using a combined machine learning and systems biology approach. In addition to his work in cancer biology, he has successfully applied this approach to California sea lions (with domoic acid toxicosis) and bottlenose dolphins (with diabetes and hemochromatosis). His work with NIST is a continuation of these projects as well as a focus on integration of other –omic data such as lipidomic and metabolomic.

Professional Awards and Recognition:

  • 1st Place Student Presentation, 43rd Annual IAAAM Conference, 2012
  • 2nd Place Poster, MUSC Student Research Day, 2012
  • 1st Place Student Presentation, 42nd Annual IAAAM Conference, 2011
  • 1st Place Poster, Department of Medicine's 5th Annual Research Day, 2010

Selected Publications:

Other Publications:

Staff Education

  • Ph.D., Biomedical Sciences, Medical University of South Carolina, Charleston, SC , 2009
  • B.S.E.S., Environmental Soil Science, The University of Georgia, Athens, GA, 2003

Staff Employment

  • Staff Scientist, MUSC Proteomics Center, Medical University of South Carolina, Charleston, SC, 11/2012 – 5/2016
  • Post-Doctoral Scholar, Nephrology Proteomics Laboratory, Medical University of South Carolina, Charleston, SC, 01/2010 - 11/2012
  • Graduate Research Assistant, Medical University of South Carolina, Charleston, SC, 8/2004 – 9/2009
  • Research Assistant, The University of Florida, Gainesville, FL, 05/2003 - 09/2003
  • Teacher Assistant and Laboratory Technician, The University of Georgia, Athens, GA, 09/2002 - 08/2004
  • Horticulture Exchange Student, Boomkwekerij Togtema; Buitenpost, Netherlands, 06/2002 - 09/2002
  • Volunteer Intern, USDA, NRCS, Louisiana State Soil Survey, Ringgold, LA, 10/2001 – 11/2001
  • Laboratory Technician, Department of Biochemistry, Vanderbilt University, Nashville, TN, 5/2001 – 9/2001

Campus

Mailing Address

United States

Mail Stop

8930

Organizational Unit

Division Name

Chemical Sciences Division

Division Code

646

Group Name

Marine Biochemical Sciences Group

Group Code

09

Access Rights

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Frank Mari

Display Name

Mari, Frank

First Name

Frank

Alternate First Name

Frank

Last Name

Mari

Alternate Last Name

Mari

Phone Number

(843) 762-8960

Email Address

CPR ID

211525

Staff Type

NIST Employee

Staff Bio

Frank Marí has worked extensively with peptides and proteins of marine origin; especially those from predatory venomous mollusks belonging to the genus Conus (cone snails), using an assortment of bioanalytical techniques to biochemically and functionally characterize components of interest. As part of these efforts, he has developed NMR-based structural techniques to study neuroactive marine peptides using nanomolar quantities directly isolated from their natural sources. Frank is also engaged in the development of mass spectrometry and bioinformatics based workflows for "venomics", a comprehensive approach for the screening and identification of neuroactive compounds from the venom of marine organisms. Through venomics, the aim is to intensify the discovery process of marine compounds of neuropharmacological importance and evaluate their potential in human health applications. Frank leads the recently created Marine Biochemical Sciences Team at Hollings Marine Laboratory. The mission of the team is to perform state-of-the-art bioanalytical measurements in samples of marine origin, particularly those samples that have environmental and human health impact.

Membership and Professional Activities

  • Member of the Society for Neuroscience, International Society on Toxinology, Biophysical Society, American Chemical Society

Awards

  • Organizer of the XII Congress of the Pan-American Section of the International Society on Toxinology, Miami Beach, Florida, 2016
  • Keynote Speaker and member of the organizing committee of the Marine Toxins Session of the XI Congress of the Pan-American Section of the International Society on Toxinology, Guarajá, Brazil, 2013
  • Faculty mentor in the NSF Undergraduate Research and Mentoring (URM) program at FAU, 2012
  • Keynote Speaker, Conodays, international meeting dedicated to cone snail research, sponsored by Conco, Zermatt, Switzerland, 2012
  • Keynote Speaker at the FAU Chemistry Club Annual Meeting, 2010
  • Profiled in Chemical Biology & Drug Design, February 2007
  • Selected Speaker, US-Japan Seminar in Marine Natural Products Research, Park City, UT, 2007
  • Selected Speaker, Gordon Research Conference in Marine Natural Products Research, Ventura, CA, 2006
  • Selected Speaker, Gordon Research Conference in Marine Natural Products Research, Ventura, CA, 2004
  • Researcher of the Year Award (Assistant Professor), Florida Atlantic University, 1997-1998
  • National Institute of Health, training fellowship, University of Massachusetts Medical Center, 1992
  • Diabetes Endocrinology Research Center, University of Massachusetts Medical Center, new pilot feasibility studies award, 1992

Selected Publications

Other Publications

Staff Education

  • Pharmacology, Postdoc, University of Massachusetts Medical Center, Worcester, 1990-1992
  • Chemistry, Ph.D., University of Massachusetts, Amherst, 1990
  • Polymer Science and Engineering, M.S., University of Massachusetts, Amherst, 1987
  • Chemistry, B.S., Universidad Simon Bolivar, Caracas, 1983

Staff Employment

  • Professor, Department of Chemistry and Biochemistry (Primary Appointment). Affiliate appointments: Department of Biomedical Sciences, College of Medicine and the Integrative Biology Ph.D. program. Memberships: Center for Molecular Biology & Biotechnology, Center of Excellence in Biomedical & Marine Biotechnology and the Neuroscience Program, 08/1993 – 12/2015
  • Visiting Scholar, University of Leuven (Fall 2009), Leuven Belgium, Laboratory of Toxicology, sponsor: Prof. Jan Tytgat, 07/2009 - 11/2009
  • Visiting Scholar, RMIT University (Spring 2010), Melbourne, Australia, Health Innovations Research Institute, Sponsor: Prof. David J. Adams, 01/2010 – 06/2010
  • Instructor of Pharmacology, University of Massachusetts Medical Center at Worcester, 10/1992 - 07/1993
  • NMR Laboratory Manager and Postdoctoral fellow, University of Massachusetts Medical Center at Worcester, 10/1990 - 09/1992
  • NMR Specialist and Consultant, Department of Food Science, University of Massachusetts at Amherst, 06/1989 - 09/1990
  • NMR Facility Manager, Polymer Science and Engineering Department/Chemistry Department, University of Massachusetts at Amherst, 05/1988 – 10/1989

Campus

Mailing Address

United States

Mail Stop

8390

Organizational Unit

Division Name

Chemical Sciences Division

Division Code

646

Group Name

Marine Biochemical Sciences Group

Group Code

09

Access Rights

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Dan Bearden

Display Name

Bearden, Dan

First Name

Daniel

Alternate First Name

Dan

Middle Name/Initial

W

Last Name

Bearden

Alternate Last Name

Bearden

Phone Number

(843) 762-8865

Email Address

CPR ID

24043

Staff Type

NIST Employee

Campus

Mailing Address

National Institute of Stds and Tech
100 Bureau Drive
Gaithersburg, MD 20899
United States

Mail Stop

8390

Organizational Unit

Division Name

Chemical Sciences Division

Division Code

646

Group Name

Marine Biochemical Sciences Group

Group Code

09

Access Rights

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Tracey Schock

Display Name

Schock, Tracey

Staff Photo

First Name

Tracey

Alternate First Name

Tracey

Middle Name/Initial

Beth Schock

Last Name

Johnston

Alternate Last Name

Schock

Phone Number

(843) 762-8921

Email Address

CPR ID

24782

Staff Type

NIST Employee

Staff Bio

Tracey's research interests have focused on the intimate cyclic relationship of oceans and humans. Her backgrounds in marine science and molecular biology followed by a shift to marine natural products chemistry (dissertation work) have facilitated a seamless transition into her current research emphasis at NIST in the field of environmental metabolomics.

Metabolomics research is a quickly growing field with broad application and a likely long-lived future for the measure of physiology or health in real time. Tracey is applying this technique to investigate effects of environmental stressors, such as chemical exposure, disease and/or abiotic changes like rise of sea water temperature, which offers the opportunity to assess systematic responses at the organismal level. The research may result in identification of novel biochemistry, potential markers of stress, information about stressor mechanisms of action, and ultimately a monitoring tool for the health of the environment. The lab has conducted metabolomics studies on a variety of conditions and organisms including oxidative stress in crustaceans, temperature effect in the coral pathogen Vibrio coralliilyticus, alternative diets for aquaculture species, and illness in green sea turtles. Nuclear magnetic resonance (NMR) has been the primary analytical platform for these analyses with immediate plans for LC/MS-based analyses in upcoming studies.

Tracey's research has an overarching aim of promoting best practices to produce high quality metabolomics data which includes stringent experimental designs, efficient and repeatable metabolite extraction, and reproducible metabolite measurements. Her current metabolomic studies include health assessments of samples collected and banked with the Pacific Islands team of the NIST Marine Environmental Specimen Bank and toxicology studies with sentinel species

Membership and Professional Activities

  • Metabolomics Society
  • Society of Environmental Toxicology and Chemistry (SETAC)
  • American Chemical Society
  • Adjunct Appointments
    - The College of Charleston
    - The Medical University of South Carolina

Staff Education

  • Ph.D., Biomedical Science, Medical University of South Carolina, 2007
  • M.S., Medical Microbiology, University of Georgia, 2001
  • B.S., Marine Biology, Southampton College, 1999

Campus

Mailing Address

National Institute of Stds and Tech
100 Bureau Drive
Gaithersburg, MD 20899
United States

Mail Stop

8390

Organizational Unit

Division Name

Chemical Sciences Division

Division Code

646

Group Name

Marine Biochemical Sciences Group

Group Code

09

Access Rights

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Janiel J. Reed

Display Name

Reed, Janiel J.

Staff Photo

First Name

Janiel

Alternate First Name

Janiel J.

Middle Name/Initial

J

Last Name

Reed

Alternate Last Name

Reed

Phone Number

(301) 975-3151

Email Address

CPR ID

12435

Title/Position

IT Specialist (System Analysis)

Staff Type

NIST Employee

Staff Bio

Janiel prepares data sets for publication by NIST. Her work has been published in many NIST Standard Reference Data products including the NIST Chemistry Webbook, MALDI Recipes, and the NIST Gas Chromatographic Method/Retention Index Database. She recently completed work with Don Burgess in creating a website dedicated to InChI-ER. A method of extending IUPAC International Chemical Identifier (InChI) to describe and identify elementary reactions. In addition, she develops software for data management and maintains several web sites including the one you're reading now :-)

Staff Education

B.S. with Honors (Summa Cum Laude), Computer Information Systems, Strayer/UMUC, March 2009

A.A. with Honors, General Studies, Montgomery College, Rockville MD, May 2004

A.A.S. with Honors, Montgomery College, Rockville MD, Jan. 2004

Staff Employment

1985-Present: IT Specialist (System Analysis), NIST

1979-1985: Computer Assistant, NIH

Campus

Mailing Address

National Institute of Stds and Tech
100 Bureau Drive
Gaithersburg, MD 20899
United States

Mail Stop

8320

Organizational Unit

Division Name

Chemical Sciences Division

Division Code

646

Group Name

Chemical Informatics Research Group

Group Code

04

Access Rights

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John Bowden

Display Name

Bowden, John

Staff Photo

First Name

John

Alternate First Name

John

Middle Name/Initial

A

Last Name

Bowden

Alternate Last Name

Bowden

Phone Number

(843) 725-4820

Email Address

CPR ID

200594

Staff Type

NIST Employee

Staff Bio

Lipids present a unique target of disease biomarkers, mainly due to the fact that they are ubiquitous and exhibit a variety of physiological roles. Lipidomics, or an examination of the lipidome using mass spectrometry, has been successfully applied for the discovery and increased understanding of human disease etiology. Parallel to humans, several wildlife species have exhibited an increase in the occurrence of pathophysiological conditions, including cancers, altered metabolism, decreased fertility, inflammation, and impaired development. Thus, I am pursuing and adapting omics-based approaches commonly employed in human disease research, such as lipidomics and metabolomics, to assess environmental health, an arena in which these approaches have rarely been adapted. Efforts have been placed to develop and tailor analytical strategies (chromatography, mass spectrometry, data informatics) for the detection of novel disease state biomarkers and to apply the developed strategies to on-going environmental studies.

My work is also focused on addressing measurement challenges associated with lipidomics. A common problem of emerging disciplines, such as lipidomics, is a lack of standardized sample preparation, quantitation and data handling protocols, often leading to a large variability when comparisons are made between analyses and/or laboratories. Our initial effort to standardize lipidomics measurements is addressed in an on-going lipidomics interlaboratory study to assess and describe the variance in methodology, quantitation and data handling across the lipidomics community using standard reference materials. Efforts to harmonize lipidomics measurement to NIST standards have focused on assessing lipid stability, constructing internal standard mixtures capable of absolute quantitation, developing data handling methods, and examining current and potentially new lipidomics-based reference materials.

Professional Awards and Recognition

  • NIST/NRC Postdoctoral Research Fellowship/Associateship, 2011-2013
  • HHMI Science for Life Graduate Mentor Award (publishing with undergraduate), 2009
  • Chemistry Department Teaching Award, University of Florida, 2006-2007
  • Graduate Student Teaching Assistant Award, College of Liberal Arts and Sciences, University of Florida, 2005-2006
  • Chemistry Department Teaching Award, University of Florida, 2003-2004

Membership and Professional Activities

  • American Society for Mass Spectrometry, 2005-Present
  • Research Experience for Undergraduates (REU) Summer Program Mentor, Research Experiences in Marine Organism Health: Resilience and Response to Environmental Change, College of Charleston, Grice Marine Laboratory, 2012-Present

Staff Education

  • Ph.D., Analytical Chemistry, University of Florida, 2003-2009
  • B.S., Chemistry, University of Florida, 1999-2003

Staff Employment

  • Research Chemist, NIST, 2013-Present
  • NIST/NRC Postdoctoral Fellow, NIST, 2011-2013
  • Postdoctoral Fellow, Saint Louis University, 2009-2011

Campus

Mailing Address

United States

Mail Stop

8390

Organizational Unit

Division Name

Chemical Sciences Division

Division Code

646

Group Name

Marine Biochemical Sciences Group

Group Code

09

Selected Publications

AN EXAMINATION OF METAL DEPOSITION DERIVED FROM AEROSPACE-RELATED ACTIVITY IN SEVERAL ENVIRONMENTAL MATRICES COLLECTED FROM WATERS SURROUNDING THE KENNEDY SPACE CENTER (KSC), FLORIDA
Influence of tissue, age, and environmental quality on global levels of genomic methylation in the American alligator (Alligator mississippiensis)
Development of an Automated Multi-Injection Shotgun Lipidomics Approach using a Triple Quadrupole Mass Spectrometer

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