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Nicholas Posey

Research Chemist (NRC postdoctoral research associate)

Nicholas Posey earned his Ph.D. in Polymer Science and Engineering synthesizing bio-inspired polymers for intracellular protein delivery applications at the University of Massachusetts, Amherst under the advisement of Gregory N. Tew before starting at NIST. Currently, Nicholas is a National Research Council (NRC) postdoctoral research associate in the Materials Science and Engineering Division in MML under the advisement of Vivek M. Prabhu.

Current Research Interests at NIST:

  • Synthesis of biodegradable, charged polymers (polyelectrolytes and polyampholytes)
  • Characterization of polymer/protein complexes in solution (dynamic light scattering)
  • Formulation of hydrogel-based biomaterials for therapeutic protein delivery applications

Previous Publications:

Posey, N. D.; Tew, G. N. Associative and Dissociative Processes in Non-covalent Polymer-Mediated Intracellular Protein Delivery. Chemistry - An Asian Journal 2018, 13, 2251-3365.

Posey, N. D.; Tew, G. N. Protein Transduction Domain Mimic (PTDM) Self-Assembly? Polymers 2018, 10, 1039.

Posey, N. D.; Hango, C.; Minter, L. M.; Tew, G. N. The Role of Cargo Binding Strength in Polymer-Mediated Intracellular Protein Delivery. Bioconjugate Chemistry, 2018, 29, 2679-2690.

Posey, N. D.; Caffrey, L. M.; Minter, L. M.; Tew, G. N. Protein Mimic Hydrophobicity Affects Intracellular Delivery but not Cargo Binding. ChemistrySelect 2016, 1, 6146-6150.

deRonde B. M.; Posey N. D.; Otter R.; Caffrey L. M.; Minter L. M.; Tew G. N. Optimal Hydrophobicity in Ring-Opening Metathesis Polymerization-Based Protein Mimics Required for siRNA Internalization. Biomacromolecules 2016, 17, 1969-1977.

Kwasny, M. T.; Watkins, C. M.; Posey, N. D.; Matta, M. E.; Tew, G. N. Functional Polyethylenes with Precisely Placed Thioethers and Sulfoniums through Thiol-Ene polymerization. Macromolecules, 2018, 51, 4280-4289.

Awards

NRC postdoctoral research associateship (2018)

U.S. Department of Education Graduate Assistance in Areas of National Need (GAANN) Fellowship (2017-2018)

NSF National Research Trainee (NRT) Fellowship (2016-2017)

Polymer Science and Engineering Department First Year Fellowship (2013)

Created December 13, 2018, Updated February 19, 2020