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Meagan Cauble (Assoc)

Biomaterials Group

meagan.cauble [at] nist.gov

(301) 975-5520

Staff Employment

(2021 – present) UMD-NIST PREP Postdoctoral Fellow

(2018 – 2021) Postdoctoral Fellow, UConn Health, Center for Cell Analysis and Modeling

(2016 – 2018) Postdoctoral Fellow, UConn Health, Department of Orthopaedic Surgery

Staff Education

Ph.D., Chemistry, University of Michigan, 2016

M.S., Chemistry, University of Michigan, 2014

B.S., Biochemistry and Molecular Biology, University of Georgia, 2011

Meagan Cauble joined the Biomaterials Group in 2021 under the direction of Sumona Sarkar. Meagan has expertise in atomic force microscopy (AFM) imaging of extracellular matrix in musculoskeletal tissues to assess altered tissue structure from disease and drug treatment. Other research projects prior to NIST include growth factor signaling in intervertebral disc cells and multiplex probe development for image-based profiling of tyrosine phosphorylation.

At NIST, Meagan is developing a cell counting method based on genome copy number. This method integrates cell cycle characterization, quantification of DNA recovery during extraction, and absolute quantification of genomic targets in droplet digital PCR to calculate a cell count.

Research Interests

Cell Therapy and Regenerative Medicine
Cell Counting and viability measurements
Cell-based reference materials
Atomic force microscopy
Characterization of spatial-dependent properties of cells

HONORS

NIDCR T90 Training Grant Recipient, UConn Health, 2019-2021
Health Center Research Advisory Council Postdoctoral Fellow Travel Grant, 2018
Rackham Graduate School Research Grant, 2016
Rackham Graduate School Travel Grant, 2016
Gordon Research Seminar Poster Award, 2016
University of Michigan Vaughn Symposium Poster Award, 2014
American Chemical Society Undergraduate Student Award, 2010-2011
Goldwater Scholar, 2010

SELECTED PUBLICATIONS

MA Cauble, NS Mancini, J Kalinowski, G Lykotrafitis, and IL Moss. Atomic force microscopy imaging for nanoscale and microscale assessments of extracellular matrix in intervertebral disc and degeneration. JOR Spine 2020 3(3):e1125.

M Cauble, P Yang, U Baumann, JM Gebauer, BG Orr, LT Duong, MM Banaszak Holl. Microstructure Dependent Binding of Pigment Epithelium Derived Factor (PEDF) to Type I Collagen Fibrils. Journal of Structural Biology 2017 199 132-139.

MA Cauble, M Muckley, M Fang, JA Fessler, K Welch, E Rothman, BG Orr, LT Duong, and MM Banaszak Holl. Estrogen depletion and drug treatment alter the microstructure of type I collagen in bone. Bone Reports 2016 5 243-251.

MA Cauble, E Rothman, K Welch, M Fang, LT Duong, BL Pennypacker, BG Orr, and MM Banaszak Holl. Alteration of Type I collagen microstructure induced by estrogen depletion can be prevented with drug treatment. BoneKEy 2015 4 697.

Full publication list can be found here: https://www.ncbi.nlm.nih.gov/myncbi/meagan.cauble.2/bibliography/public/