Jayan Rammohan is a National Research Council (NRC) postdoctoral research scientist on the Engineering Biology team at the National Institute for Standards and Technology (NIST). Jayan is making quantitative measurements to facilitate the emergence of biology as an engineering discipline. For example, he is measuring bacterial transcription kinetics by single-molecule fluorescence microscopy, in order to develop metrics for information processing in engineered biological systems. To this end, he employs a broad range of experimental and theoretical tools including fluorescent labeling of RNA transcripts in fixed and live cells, microfluidic devices for high-throughput single-cell analysis, and probability theory for extracting meaning from distributions of stochastic gene expression. Additionally, Jayan is actively exploring current issues in the fields of technology transfer, intellectual property, regulatory affairs, public policy and education, in order to identify stakeholder needs and translate synthetic biology research into commercial applications.
Jayan received his BS and MS in Biomedical Engineering from Case Western Reserve University, where he characterized nanoscale polymer biomaterials for applications to orthopedic tissue engineering. During his PhD in Molecular Biophysics from Washington University in St. Louis, Jayan studied the regulatory mechanisms of transcription factors essential to Mycobacterium tuberculosis. Jayan worked as a postdoctoral associate in the Department of Biological Engineering at MIT before receiving an NRC Postdoctoral Research Associateship to work at NIST.