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Benjamin Scott

Ben is a postdoctoral associate at the National Institute of Standards and Technology (NIST). His research is focused on engineering G protein-coupled receptors (GPCRs) and associated signaling pathways. These synthetic gene circuits have applications as biosensors for valuable compounds, new drug discovery platforms, and to create cell-based therapies.

Ben holds a Bachelor’s degree in Life Sciences from McMaster University, where he first developed an interest in the origins of life and protein engineering. He completed a Master’s degree in Medical Sciences at McMaster, and a PhD at the University of Toronto focusing on synthetic biology. Passionate about trainee engagement, he founded SynBio Canada, McMaster University’s first iGEM team, and has led several student unions.

Selected Publications

Scott BM, Chen SK, Bhattacharyya N, Moalim AY, Plotnikov SV, Heon E, Peisajovich SG, Chang BSW. (2019) Coupling of Human Rhodopsin to a Yeast Signaling Pathway Enables Characterization of Mutations Associated with Retinal Disease. Genetics, 211(2), 597-615. *selected as a Highlighted Article

 Di Roberto RB, Scott BM, Peisajovich SG. (2017) Directed Evolution Methods to Rewire Signaling Networks. Methods in Molecular Biology, 1596, 321-337.

 Scott BM, Matochko WL, Gierczak RF, Bhakta V, Derda R, Sheffield WP. (2014) Phage Display of the Serpin Alpha-1 Proteinase Inhibitor Randomized at Consecutive Residues in the Reactive Centre Loop and Biopanned with or without Thrombin. PLOS ONE, 9(1): e84491.

 Google scholar


Created July 30, 2019, Updated December 13, 2019