This paper describes statistical experimental design approach of identifying sources of Pu contamination throughout analysis of shellfish at the National Institute of Standards and Technology (NIST). The potential sources of contamination included the fume hood, the glassware, and reagents used. Ordinarily, over 200 experiments would have been performed in order to isolate the contamination sources for 8 factors. Since this commonly used design is not an efficient use of time and resources, an orthogonal design of experiment (ODEX) was constructed, subsequent data was analyzed using Exploratory Date Analysis (EDA). ODEX/EDA narrowed the 200+ experiments to a very manageable 16. This design made it possible to identify the sources and interactions of sources of contamination in a timely and cost effective manner.
Citation: Journal for Radioanalytical and Nuclear Chemistry
Pub Type: Journals
contamination, EDA, ODEX, plutonium, SRM