Application of microreactor technologies enable improved safety, selectivity and yield in a range of chemical reactions in addition to new measurement methods that are often faster, cheaper and more accurate than traditional methods. In this study we have considered a model system, Candida antartica Lipase B (CAL B) catalyzed polycaprolactone synthesis from -caprolactone. CAL B was immobilized on polymethyl methacrylate support and was loaded in the microchannel reactors. Raman spectroscopy, Nuclear Magnetic resonance (NMR) and Gel permeation Chromatography (GPC) were used to characterize the reaction products. The monomer conversion in microreactors was faster than that observed in the batch reactors.
Proceedings Title: American Chemical Society Spring 2010 National Meeting
Conference Dates: March 21-25, 2010
Conference Location: San Francisco, CA
Pub Type: Conferences
microreactor, enzyme catalysis, ring opening polymerization