Novel Reduced Pressure-Balance Syringe for Chromatographic Analysis

Published

November 19, 2010

Author(s)

Bret Windom, Thomas J. Bruno

Abstract

When withdrawing a fluid sample from an apparatus at reduced pressures for additional chromatographic analyses, a gas tight plunger syringe proves ineffective as it does not create a substantial pressure differential to pull a fluid from a reduced pressure environment. Resulting from motivation to analyze distillate fractions from a reduced pressure advanced distillation curve (ADC) apparatus, a device was developed allowing one to withdraw precise amounts of sample from an apparatus operating at sub-ambient pressures. The new device uses an external vacuum source to evacuate a syringe barrel, extracting fluids from a chamber at pressures as low as 0.5 kPa. To demonstrate the operation of the newly developed device, 10 υl of distillate fraction from the reduced pressure ADC apparatus were withdrawn and analyzed by gas chromatography mass spectrometry. Distillate extraction and analyses were performed on two fluids, a predefined validation mixture and commercial soy based biodiesel fuel. The new device is not limited to reduced pressure distillations and may be useful for a variety of applications in which further chemical/compositional analyses are desired on a fluid contained in a reduced pressure environment.

Citation

Journal of Chromatography A

Volume

1217

Issue

47

Pub Type

Journals

Keywords

chromatography, sampling, syringe, vacuum

Citation

Windom, B. and Bruno, T. (2010), Novel Reduced Pressure-Balance Syringe for Chromatographic Analysis, Journal of Chromatography A (Accessed April 20, 2024)