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Supporting Anti-Doping Efforts in International Sports

NIST SRM 2926 Recombinant Human Insulin-like Growth Factor 1 (Frozen)

SRM 2926

What: SRM 2926 is a frozen aqueous solution of recombinant human insulin-like growth factor 1 (IGF-1).  The SRM consists of three vials, each containing approximately 0.25 mL of frozen solution.

Why:  IGF-1 is measured in human serum for clinical diagnostic purposes as well as by the sports anti-doping community to detect abuse of human growth hormone.

Who: SRM 2926 is intended to be used to support quantification of IGF-1 in human serum using LC-MS/MS measurement methods.

How:  This SRM can be used to assess the accuracy of calibrators and control materials used for the quantification of IGF-1 using LC-MS/MS.  An international certified reference material for human IGF-1 should improve the equivalence of measurement results between different methods and across geographic locations.

Released February 4, 2020, Updated February 3, 2020