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Metrology

Projects/Programs

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Charpy Machine Verification Program

Ongoing

WARNING RELATED TO TESTING SUPER-HIGH ENERGY SPECIMENS The steel currently used by NIST for the production of super-high energy reference Charpy specimens tends

Chemical Metrology for Metals, Ores, and Related Materials

Ongoing

A wide range of industrial sectors and their customers and suppliers are involved directly with NIST in the prioritization and development of certified

Chemical Metrology for Polymers Manufacturing

Ongoing

Chemical metrology for polymers manufacturing is a new area of endeavor for the Chemical Sciences Division. At the outset, efforts have involved mostly

Clinical Measurements Quality Assurance Program

Ongoing

The National Institute of Standards and Technology (NIST) established the Clinical Measurements Quality Assurance Program (ClinQAP) to support the measurement

CODATA values of the fundamental physical constants

Ongoing

Every four years, the Committee on Data for Science and Technology (CODATA) issues recommended values of the fundamental physical constants. The values are

Combinatorial Approaches to Thin Film Nanomaterials

Completed

Our goal is to develop combinatorial library approaches for measuring and optimizing the effect of substrate chemical functionalization on the structure and

Compatibility Assessment and Bias Estimation for Standard Reference Materials

Ongoing

NIST produces a number of food-matrix Standard Reference Materials. A problem that frequently occurs in their analysis is one of assessing compatibility of data

Continuing Support of Cement Manufacturing

Ongoing

Cement manufacturers and their customers rely on the NIST Portland cement SRMs for laboratory qualification under ASTM International C 114-07 Standard Test

Cruciform Multiaxial Mechanical Testing

Ongoing

The cruciform mechanical test is widely used to measure the multiaxial deformation behavior of materials. Standardization of this technique would have

Crystal Plasticity Modeling of Yield Surface Evolution

Crystal Plasticity Modeling calculates multiaxial mechanical constitutive behavior by treating the sample as an interacting aggregate of single crystals that

Data Science

Ongoing

The NIST Information Access Division (IAD) initiated a Data Science Research Program (DSRP) aimed to advance the measurement science for big data and data

Detecting Change Points in Surface Temperature Records

Ongoing

The long records (sometimes over 100 years) of surface temperatures available from meteorological monitoring stations in the Unites States can be a valuable

Development of a Collagen Fibril Reference Material for Reproducible Cell Response

Ongoing

An important determinant of cellular response to drugs and toxins is the chemical and physical nature of the extracellular matrix (ECM) to which cells are

Development of Methods for Measurement of Vitamin D and its Metabolites in Foods, Fortified Foods, and Dietary Supplements

Ongoing

Vitamin D is a fat-soluble vitamin that is essential for bone health. Vitamin D deficiency is associated with muscle weakness and osteoporosis and can

Development of Novel Non-Contact Sampling Tools and Techniques

Ongoing

We are investigating non-contact methods for high volume, high throughput, and high transfer/transport efficiency screening and documenting appropriate testing

Development of Reference Measurement Procedures and Reference Materials for Creatinine

Ongoing

Chronic kidney disease (CKD) is a growing problem in the U.S., and current estimates suggest that more than 20 million Americans are affected by this disease

Development of Reference Methods and Reference Materials for the Determination of Hormones in Human Serum

Ongoing

Hormones are chemical messengers that regulate many life functions, and deviations from normal levels can indicate serious health problems. Measurement of

Development of Reference Methods and Reference Materials for the Determination of Cardiac Troponin I in Human Serum

Ongoing

Cardiac troponin I (cTnI) is considered the 'gold standard' for the diagnosis of myocardial infarction and the assessment of cardiac damage. Yet this clinical

Development of SRM 2669 for Accurate Assessment of Arsenic Exposure

Ongoing

The National Institute of Standards and Technology (NIST), in collaboration with the Centers for Disease Control and Prevention (CDC), has developed Standard

Development of SRM 955c Toxic Elements in Caprine Blood

Ongoing

Environmental and occupational exposure to toxic metals is assessed through whole blood analysis. Due to advances in instrument technology, clinical

Development of SRMs 2668 and 3668 for Accurate Assessment of Exposure to Toxic Elements and Anions

Ongoing

As part of a multi-year interagency agreement between the National Institute of Standards and Technology (NIST) and the Centers for Disease Control and

Development of SRMs for Serum Proteomics

Ongoing

Serum proteomics, the detection and measurement of as many proteins in a serum sample as possible, could be an important element of personalized medicine

Development of Standards for the World Meteorological Organization, Global Atmosphere Watch Program

Ongoing

The presence of volatile organic compounds (VOCs), which include hydrocarbons, monoterpenes and oxygenates, in the atmosphere has become important to climate

Dietary Supplements Laboratory Quality Assurance Program (DSQAP)

Ongoing

The National Institute of Standards and Technology (NIST), in collaboration with the National Institutes of Health (NIH) Office of Dietary Supplements (ODS)

Picture of PBD set up for wavelength measurement

Diffraction Metrology and Standards

Ongoing

Our objective is the development of Standard Reference Materials (SRMs) and quantitative, reproducible, and accurate measurement methods for characterization of

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