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Chemistry

Projects/Programs

Keyword

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Consistency Analysis and Uncertainty in ‘omic Data

Ongoing

As ‘omics moves into industrial and commercial applications, there is a need for quality and process control to ensure safety and efficacy of products and

Continuing Support of Cement Manufacturing

Ongoing

Cement manufacturers and their customers rely on the NIST Portland cement SRMs for laboratory qualification under ASTM International C 114-07 Standard Test

Cover of the ASME International Steam Tables for Industrial Use, Third Edition

Contributions to International Standards on the Properties of Water

Ongoing

Researchers in the Applied Chemicals and Materials Division play a leading role in the development of international standards for the properties of water. This

Data and Computational Tools for Advanced Materials Design: Structural Materials Applications - Cobalt Based Superalloys

Ongoing

The development of a materials innovation infrastructure (MII) that will enable rapid and significant reductions in the development time for new materials with

Density Functional Tight Binding Methods

Ongoing

Density Functional Tight Binding (DFTB) methods have been shown to be capable of producing reliable molecular structures and energetics at a significantly

Development of Biomarker-based Systems for Cancer Detection and Therapy

Ongoing

Biomarkers play an increasingly important role in disease detection and treatment. As one of the Biomarker Reference Laboratories (BRLs) in the Early Detection

Development of Enhanced mRNA Amplification Using Microfluidics

Ongoing

In conjunction with NCI/NIH, NIST is developing methods to improve mRNA amplification from small biological samples. Typical sample processing requires

Development of Methods for Measurement of Vitamin D and its Metabolites in Foods, Fortified Foods, and Dietary Supplements

Ongoing

Vitamin D is a fat-soluble vitamin that is essential for bone health. Vitamin D deficiency is associated with muscle weakness and osteoporosis and can

Development of Proteomics-Based Methods for Protein Quantification

Ongoing

NIST is developing methods for the quantification of clinically-relevant protein biomarkers by mass spectrometry. Some methods are intended to establish

Development of Reference Methods and Reference Materials for the Determination of Cardiac Troponin I in Human Serum

Ongoing

Cardiac troponin I (cTnI) is considered the 'gold standard' for the diagnosis of myocardial infarction and the assessment of cardiac damage. Yet this clinical

Development of Reference Methods and Reference Materials for the Determination of Hormones in Human Serum

Ongoing

Hormones are chemical messengers that regulate many life functions, and deviations from normal levels can indicate serious health problems. Measurement of

Development of Reference Methods and Reference Materials for Proteins

Ongoing

A number of proteins show promise as potential markers of health or disease, and commercial assays are being developed for these proteins. For example

Development of SRM 2669 for Accurate Assessment of Arsenic Exposure

Ongoing

The National Institute of Standards and Technology (NIST), in collaboration with the Centers for Disease Control and Prevention (CDC), has developed Standard

Development of SRMs 2668 and 3668 for Accurate Assessment of Exposure to Toxic Elements and Anions

Ongoing

As part of a multi-year interagency agreement between the National Institute of Standards and Technology (NIST) and the Centers for Disease Control and

Development of SRMs for Serum Proteomics

Ongoing

Serum proteomics, the detection and measurement of as many proteins in a serum sample as possible, could be an important element of personalized medicine

Dietary Supplements Laboratory Quality Assurance Program (DSQAP)

Ongoing

The National Institute of Standards and Technology (NIST), in collaboration with the National Institutes of Health (NIH) Office of Dietary Supplements (ODS)

Differential absorption LIDAR for the detection and quantification of greenhouse gases

Ongoing

We are developing a method for accurately quantifying greenhouse gas emissions from natural and anthropogenic sources and sinks to meet the requirements for

Digital PCR

Ongoing

Digital PCR (dPCR) is a method used to quantify nucleic acids (DNA, RNA, cDNA). At NIST we are using microfluidic and emulsion-based dPCR platforms for

DNA Profiling Standard Reference Materials

Ongoing

NIST has produced several PCR-based DNA Profiling Standard Reference Materials (SRMs) for the forensic community. The primary uses of these materials are

Ecogenotoxicity Measurements of Nanoparticles

Ongoing

As a result of their novel properties, nanoparticles are expected to be produced and incorporated into consumer products at exponentially increasing quantities

Effect of Partial Charge Calculation Method on Adsorption Thermodynamics in Metal-organic Frameworks

Ongoing

In classical molecular simulations, electrostatic contributions to the potential energy are typically accounted for by assigning partial charges to some or all

Electrochemical Processes

Ongoing

In this project we are developing in situ measurements relevant to the electrochemical fabrication, processing, and application of nanostructured materials and

Electron Ionization Library Component of the NIST/EPA/NIH Mass Spectral Library and NIST GC Retention Index Database

Ongoing

The National Institute of Standards and Technology (NIST) has developed and maintains evaluated libraries of reference data for the identification of chemicals

Engineering and Optical Characterization of Magnetic Nanoparticles (MNPs)

Ongoing

This project comprises of two complimentary components: 1.) the controlled synthesis of selectively engineered magnetic nanoparticles (MNPs) in support of the

Evaluating the Quality of Cell Counting Methods: Experimental Design and Statistical Analysis

Ongoing

Cell counting is a fundamental measurement in biotechnology and is especially important for novel cell-based therapies, where cell count-based measurements are

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