DETERMINATION OF PERFLUORINATED COMPOUNDS IN STANDARD REFERENCE MATERIALS USING LC/MS/MS

 

Jessica Reiner1, Jennifer Keller1, John Kucklick1, Michele Shantz2

1National Institute of Standards and Technology, Hollings Marine Laboratory, 331 Ft. Johnson Rd., Charleston, SC, USA 2National Institute of Standards and Technology, 100 Bureau Dr., Gaithersburg, MD, USA

 

Perfluorinated compounds (PFCs), used in various consumer goods, have been under increased scrutiny and intense environmental research for the past 10 years. They have been detected as an environmental contaminant in both biotic and abiotic systems and are considered widespread, being detected in remote locations like the Canadian Arctic. Monitoring studies have shown PFCs are globally distributed and should be ranked among other persistent organohalogen compounds like polychlorinated biphenyls (PCBs). PFCs include a wide range of ionic and neutral species that contain the perfluorinated alkyl moiety and one of the hardest challenges is measuring PFCs accurately using liquid chromatography with tandem mass spectrometry detection (LC/MS/MS). The analysis and quantification of PFCs in a variety of matrices has proven to be very difficult. In 2005 the first interlaboratory comparison on PFC measurements was conducted. Laboratory agreements were poor for most PFCs and a plea for reference materials was expressed by the analytical community. Improved methods have been developed over the past few years and the analysis of candidate reference material is ongoing. Future monitoring data are likely to be used as a basis for regulatory decisions and the PFC values generated for NIST Standard Reference Materials (SRM) will provide researchers with the tools to ensure accurate, precise, and reproducible data. The current study was carried out to provide measurements for PFCs in selected SRMs.

 

 

 

Category: Chemistry

Mentor:  Michele Schantz

Division: CSTL, Analytical Chemistry (839.02)

Building: Hollings Marine Laboratory, 331 Fort Johnson Rd. Charleston, SC 29412

Phone:  843-762-8835

Fax:  843-762-8737

Email: jessica.reiner@nist.gov

Membership in Sigma Xi:  Neither author nor mentor