Design and Application of Microfluidic System for

Amphiphilic Block Copolymer Formulation

 

Kazunori Iida, Thomas Q. Chastek, and Kathryn L. Beers

 

The aim of this project is to develop a synthetic strategy with integrated characterization techniques for block copolymer libraries using a microfludic chip. Thiolene-based microfluidic chips recently developed at NIST show better performance in terms of compatibility with organic solvents than other soft materials, however there are still limitations to device stability at the elevated temperatures necessary for controlled synthesis of many block copolymer segments.

We designed and built a microfluidic chip using aluminum sealed with a thin polyimide film. We performed controlled radical polymerization on this aluminum-based chip at temperatures up to 90C for periods up to 24 hours. The desired homo- and block-copolymers were obtained with excellent control of molecular mass and molecular mass distribution using atom transfer radical polymerization (ATRP). We are also developing this system for integrated, direct monitoring using dynamic light scattering, Raman spectroscopy, or near-IR spectroscopy.

 

Author: Kazunori Iida

Mentor: Kathryn L. Beers

Division; Polymer (854)

Bldg  224, Room: B 216

Mail Stop: 8542

Telephone: 5228

Fax: 4924

e-mail: kiida@nist.gov

Sigma Xi member: No

Category: Materials, Chemistry