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You searched on: Topic Area: Life Sciences Research Sorted by: title

Displaying records 21 to 30 of 153 records.
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21. Combinatorial Screening of Hydrogel Scaffolds for 3D Cell Culture
Topic: Life Sciences Research
Published: 5/2/2011
Authors: Kaushik Chatterjee, Marian F Young, Carl George Simon Jr.
Abstract: Optimizing cell-material interactions is critical towards maximizing regeneration in tissue engineering. Combinatorial and high-throughput (CHT) methods can be used to systematically screen tissue scaffolds to identify optimal biomaterial properties ...

22. Comparison of Reagents for Shape Analysis of Fixed Cells by Automated Fluorescence Microscopy
Topic: Life Sciences Research
Published: 4/1/2003
Authors: John T Elliott, Alessandro Tona, Anne L Plant
Abstract: Background: Cell size and shape have been implicated as potentiators intracellular signaling events and as indicator of abnormal cell behavior. Automated microscopy and image analysis can provide quantitative information about the size and shape of ...

23. Conformational Changes in the Crystal Structure of Rat Glutathione Transferase M1-1 with Global Substitution of 3-Fluorotyrosine for Tyrosine
Topic: Life Sciences Research
Published: 8/14/1998
Authors: G Xiao, J F Parsons, K Tesh, R N Armstrong, G L. Gilliland
Abstract: The structure of the tetradeca-(3-fluorotyrosyl) M1-1 GSH transferase (3-Ftyr GSH transferase), a protein in which tyrosine residues are globally substituted by 3-fluorotyrosines, has been determined at 2.2 resolution. This variant was produced t ...

24. Crystal Structure and Amino Acid Sequence of Wolinella Succinogenes L-Asparaginase
Topic: Life Sciences Research
Published: 10/1/1996
Authors: J Lubkowski, G J Palm, G L. Gilliland, C Derst, K H Rohn, A Wlodawer

25. Crystal Structure of Escherichia coli Uracil DNA Glycosylase and Its Complexes with Uracil and Glycerol: Structure and Glycosylase Mechanism Revisited
Topic: Life Sciences Research
Published: 4/1/1999
Authors: G Xiao, M. Tordova, J. Jagadeesh, A C Drohat, J T. Stivers, G L. Gilliland

26. Crystal Structure of Tetradeca-(3-Fluorotyrosyl)-Glutathione Transferase
Topic: Life Sciences Research
Published: 10/1/1997
Authors: G Xiao, J F Parsons, R N Armstrong, G L. Gilliland

27. Crystal Structure of apo-cellular Retinoic Acid-Binding Protein Type II (R111M) Suggests a Mechanism of Ligand Entry
Topic: Life Sciences Research
Published: 5/8/1998
Authors: X. Chen, M Tordova, G L. Gilliland, Lili Wang, Y Li, H. Yan, X. Ji

28. Crystal Structure of the Complex Between Thrombin and the Central "E" Region of Fibrin
Topic: Life Sciences Research
Published: 3/2/2004
Authors: I Pechik, J Madrazo, M W Mosesson, I Hernandez, G L. Gilliland, L Medved
Abstract: Non-substrate interactions of thrombin with fibrin play an important role in modulating its procoagulant activity. To establish the structural basis for these interactions, we crystallized PPACK-inhibited thrombin in complex with a fragment, Eht , c ...

29. Crystal Structure of the Escherichia Coli YcdX Protein Reveals a Trinuclear Zinc Active Site
Topic: Life Sciences Research
Published: 5/1/2003
Authors: A Teplyakov, G Obmolova, P P Khil, A J Howard, R D Camerini-Otero, G L. Gilliland
Abstract: The ycdX gene of Escherichia coli encodes the protein of 27 kDa molecular weight that belongs to the PHP superfamily of proteins that have diverse functions. This superfamily includes several types of DNA polymerases (namely the a-subunit of bacteria ...

30. Crystal Structure of the YchF Protein Reveals Binding Sites for GTP and Nucleic Acid
Topic: Life Sciences Research
Published: 7/1/2003
Authors: A Teplyakov, G Obmolova, S Y Chu, J Toedt, E Eisenstein, A J Howard, G L. Gilliland
Abstract: The bacterial protein encoded by the gene ychF is 1 of 11 universally conserved GTPases, and the only one whose function is unknown. The crystal structure determination of YchF was sought to help with the the functional assignment of the protein. ...

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