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Topic Area: Life Sciences Research
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Displaying records 241 to 250 of 269 records.
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241. The Cockayne Syndrome Group B Gene Product is Involved in Cellular Repair of 8-Hydroxyadenine in DNA
Topic: Life Sciences Research
Published: 8/23/2002
Authors: J Tuo, Pawel Jaruga, H Rodriguez, M Miral Dizdar, V. Bohr
Abstract: Cockayne syndrome (CS) is a human disease characterized by sensitivity to sunlight, severe neurological abnormalities and accelerated aging. CS has two complementation groups, CS-A and CS-B. The CSB gene encodes the CSB protein with 1493 amino acid ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830310

242. The Cockayne Syndrome Group B Gene Product is Involved in General Genome Base Excision Repair of 8-hydroxyguanine in DNA
Topic: Life Sciences Research
Published: 12/7/2001
Authors: J Tuo, M Muftuoglu, C Chen, Pawel Jaruga, R R Selzer, R M Brosh, H Rodriguez, M Miral Dizdar, V. Bohr
Abstract: Cockayne Syndrome (CS) is a human genetic disorder with two complementation groups, CS-A and CS-B. The CSB gene product is involved in transcription-coupled repair of DNA damage but may participate in other pathways of DNA metabolism. The present s ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830260

243. The Crystal Structure of Chorismate Lyase Shows a New Fold and a Tightly Retained Product
Topic: Life Sciences Research
Published: 8/15/2001
Authors: David Travis Gallagher, M P. Mayhew, Marcia J Holden, A J Howard, K J Kim, V L. Vilker
Abstract: The enzyme chorismate lyase (CL) catalyzes the removal of pyruvate from chorismate to produce 4-hydroxy benzoate (4HB) for the ubiquinone pathway. In Escherichia coli, CL is monomeric with 164 residues; we have determined the structure of the CL pro ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830208

244. The Crystal Structure of the Disulfide-stabilized Fv Fragment of Anticancer Antibody B1: Conformational Influence of an Engineered Disulfide Bond
Topic: Life Sciences Research
Published: 5/1/1998
Authors: O Almog, I Benhar, M Tordova, I Pastan, G L. Gilliland
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=901564

245. The Effect of Experimental Conditions on the Levels of Oxidatively Modified Bases in DNA as Measured by Gas Chromatography- Mass Spectrometry. How Many Modified Bases Are Involved? Prepurification or Not?
Topic: Life Sciences Research
Published: 12/1/1999
Authors: S. Senturker, M Miral Dizdar
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=100608

246. The Electronic Spectra of the H and OH Adducts of Cytosine
Topic: Life Sciences Research
Published: 5/29/1997
Authors: Morris Krauss, R Osman
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=100245

247. The Electronic Spectrum of the Prephenate Dianion. An Experimental and Theoretical (MD/QM) Comparison
Topic: Life Sciences Research
Published: 8/2/2000
Authors: A. E. Roitberg, S. E. Worthington, Marcia J Holden, M P. Mayhew, Morris Krauss
Abstract: Prephenate is the product of a Claisen rearrangement of chorismate. The enzyme chorismate mutase (CM from B. subtilis) accelerates the reaction by a factor of 10^u6^. The standard method for quantifying prephenate measures the electronic absorption ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830141

248. The Escherichia coli YdcF binds S-adenosyl-L-methionine and adopts an alpha/beta fold characteristic of nucleotide-utilizing enzymes
Topic: Life Sciences Research
Published: 7/1/2008
Authors: Kinlin L. Chao, Kap Lim, C Lehmann, V Doseeva, A J Howard, Frederick P. Schwarz, Osnat Herzberg
Abstract: The crystal structure of YdcF at a resolution of 0.18 nm reveals a fold of the adenine nucleotide α hydrolase-like family. Following the structural clues, a nucleotide binding screen was carried out employing isothermal titration calorimetry. Th ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=832211

249. The Role of Water in the Thermodynamics of Drug Binding to Cyclodextrin
Topic: Life Sciences Research
Published: 7/1/2007
Authors: Niya Tordorova, Frederick P. Schwarz
Abstract: The thermodynamic parameters, DBGo, DBHo, and DBSo, of the drugs flurbiprofen (FLP), nabumetone (NAB), and naproxen (NPX) binding to b-cyclodextrin (bCD) and to g-cyclodextrin (gCD) in 0.10 M sodium phosphate buffer were determined from isothermal ti ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830570

250. The Stiffness of Collagen Fibrils Influences Vascular Smooth Muscle Cell Phenotype
Topic: Life Sciences Research
Published: 3/1/2007
Authors: Dennis P. McDaniel, Gordon Allan Shaw, John T Elliott, Kiran Bhadriraju, Curtis W Meuse, Koo-Hyun Chung, Anne L Plant
Abstract: Cells receive signals from the extracellular matrix through receptor-dependent interactions, but they are also influenced by the mechanical properties of the matrix. While bulk properties of substrates have been shown to effect cell behavior, we sho ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830514



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