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Displaying records 1 to 10 of 153 records.
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1. SVClassify: a method to use multiple datasets to classify candidate structural variants into true positives and false positives
Topic: Life Sciences Research
Published: 1/16/2016
Authors: Justin M Zook, Hemang M. Parikh, Desu Chen, Hariharan K Iyer, Marc L Salit, Wolfgang Losert
Abstract: The human genome contains variants ranging in size from small single nucleotide polymorphisms (SNPs) to large structural variants (SVs). While high-quality benchmark small variant calls have recently been developed by the Genome in a Bottle Consorti ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=918034

2. ASTM Workshop on Standards & Measurements for Tissue Engineering Scaffolds
Topic: Life Sciences Research
Published: 1/1/2016
Authors: Carl George Simon Jr., John Test, Michael Yaszemski, Reto Luginbuehl, Anthony Ratcliffe, Paul Tomlins
Abstract: A ,Workshop on Standards & Measurements for Tissue Engineering ScaffoldsŠ was held on May 21, 2013 and was sponsored by the American Society of Testing and Materials International (ASTM International) in Indianapolis, IN. The purpose of the work ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915255

3. Optimization of Next-Generation Sequencing Informatics Pipelines for Clinical Laboratory Practice
Topic: Life Sciences Research
Published: 7/8/2015
Authors: Justin M Zook, Amy Gargis, Lisa Kalman, Ira Lubin, Marc L Salit
Abstract: We direct your readers' attention to the principles and guidelines (see Supplementary Guidelines) developed by the Next-generation Sequencing: Standardization of Clinical Testing II (Nex-StoCT II) informatics workgroup, which was convened by the Cent ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=916037

4. Best Practices for Evaluating Single Nucleotide Variant Calling Methods for Microbial Genomics
Topic: Life Sciences Research
Published: 7/7/2015
Authors: Nathanael D Olson, Steven P Lund, Rebecca Colman, Jeffery T. Foster, Jason W. Sahl, James M. Schupp, Paul Keim, Jayne B Morrow, Marc L Salit, Justin M Zook
Abstract: Innovations in sequencing technologies have allowed biologists to make incredible advances in understanding biological systems. As experience grows, researchers increasingly recognize that analyzing the wealth of data provided by these new sequen ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=918229

5. Quantitative scheme for full-field polarization rotating fluorescence microscopy (PROM) using a liquid crystal variable retarder
Topic: Life Sciences Research
Published: 5/14/2015
Authors: John F. Lesoine, Ji Y. Lee, Hyeong G. Kang, Matthew Lawrence Clarke, Robert C. Chang, Ralph Nossal, Jeeseong Hwang
Abstract: We introduce real-time, full-field, polarization rotating fluorescence microscopy (PROM) to monitor the absorption dipole orientations of fluorescent molecules. A quarter-wave plate, in combination with a liquid crystal variable retarder (LCVR ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908548

6. Validated Open Source Nanofiber Diameter Measurement Tool
Topic: Life Sciences Research
Published: 4/30/2015
Authors: Nathan Alexander Hotaling, Kapil Bharti, Haydn Kriel, Carl George Simon Jr.
Abstract: Despite the growing use of nanofiber scaffolds for tissue engineering applications, there is not a validated, readily available (commercial or open source) solution for rapid, automated analysis of nanofiber diameter from scanning electron microscope ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=917542

7. Quantitative Mass Spectrometry Measurements Reveal Stoichiometry of Principal Postsynaptic Density Protein Components
Topic: Life Sciences Research
Published: 4/28/2015
Authors: Mark S Lowenthal, Sanford Philip Markey, Ayse Dosemeci
Abstract: Quantitative studies are presented of postsynaptic density (PSD) fractions from rat cerebral cortex with the ultimate goal of defining the average copy numbers of proteins in the PSD complex. Highly specific and selective isotope dilution mass spectr ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=917230

8. The Art in Science of MicroTAS: the 2014 issue
Topic: Life Sciences Research
Published: 4/14/2015
Author: Darwin R Reyes-Hernandez
Abstract: For the 7th year in a row the Art in Science award competition, sponsored by Lab on a Chip and the National Institute of Standards and Technology (NIST), took place at the 18th International Conference of Miniaturized Systems for Chemistry and Life S ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=918292

9. An analytical framework for optimizing variant discovery from personal genomes
Topic: Life Sciences Research
Published: 2/25/2015
Authors: Justin M Zook, Gareth Highnam, Jason Wang, Dean Kusler, Vinaya Vijayan, Nir Leibovich, David Mittelman
Abstract: The standardization and performance testing of analysis tools is a prerequisite to widespread adoption of high-throughput sequencing, particularly in the clinic. However, performance testing is currently complicated by the paucity of standards and co ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=916355

10. Application of NMR-based Metabolomics for Environmental Assessment in the Great Lakes using Zebra Mussel (Dreissena polymorpha) polymorpha)
Topic: Life Sciences Research
Published: 2/21/2015
Authors: Miki Watanabe, Katherine Meyer, Tyler Jackson, Tracey Beth Schock Schock, Ed Johnson, Daniel W Bearden
Abstract: Zebra mussel, Dreissena polymorpha, in the Great Lakes is being monitored as a bio-indicator organism for environmental health effects by the National Oceanic and Atmospheric Administration‰s Mussel Watch program. In order to monitor the enviro ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=916464



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